Key features and details
- Rabbit polyclonal to HLA Class II DR4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-HLA Class II DR4 antibody
DescriptionRabbit polyclonal to HLA Class II DR4
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Monkey
Recombinant protein fragment corresponding to a region within amino acids 1 and 262 of Human HLA Class II DR4 (NP_068818).
- Raji whole cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab98106 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 30 kDa.|
RelevanceHLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
Cellular localizationMembrane; single pass type I membrane protein.
- HLA DR4 antibody
- HLA DRA antibody
- HLA DRB antibody
ab98106 has not yet been referenced specifically in any publications.