Overview

  • Product name

    Anti-HLA Class II DR4 antibody
  • Description

    Rabbit polyclonal to HLA Class II DR4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 1 and 262 of Human HLA Class II DR4 (NP_068818).

  • Positive control

    • Raji whole cell lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98106 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 30 kDa.

Target

  • Relevance

    HLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
  • Cellular localization

    Membrane; single pass type I membrane protein.
  • Database links

  • Alternative names

    • HLA DR4 antibody
    • HLA DRA antibody
    • HLA DRB antibody
    • HLADR4 antibody
    • Major histocompatibility complex class II DR4 antibody
    • MHC class II antigen DR antibody
    see all

Images

  • Anti-HLA Class II DR4 antibody (ab98106) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size: 30 kDa



    12% SDS PAGE

References

ab98106 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab98106.
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