Anti-HLA DR + HLA DP antibody [MEM-136] (Allophycocyanin) (ab239291)

Overview

  • Product name

    Anti-HLA DR + HLA DP antibody [MEM-136] (Allophycocyanin)
    See all HLA DR + HLA DP primary antibodies
  • Description

    Mouse monoclonal [MEM-136] to HLA DR + HLA DP (Allophycocyanin)
  • Host species

    Mouse
  • Conjugation

    Allophycocyanin. Ex: 645nm, Em: 660nm
  • Specificity

    ab239291 recognizes a common epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit.
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human HLA DR + HLA DP. (PHA-activated peripheral blood lymphocytes).

  • Positive control

    • Flow Cyt: Human peripheral blood.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage buffer

    Preservative: 0.0975% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Size exclusion
  • Purification notes

    Purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
  • Clonality

    Monoclonal
  • Clone number

    MEM-136
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab239291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells.

(or 100 µl of whole blood).

Target

  • Relevance

    Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
  • Cellular localization

    Cell Membrane; Single pass type I membrane protein
  • Database links

  • Alternative names

    • HLA DP antibody
    • HLA DR antibody
    • MHC Class II antibody

Images

  • Flow cytometric analysis of human peripheral blood labeling HLA DR + HLA DP with ab239291. Surface staining. Gated on leukocytes.

References

ab239291 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab239291.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up