Key features and details
- Mouse monoclonal [HL-38] to HLA DR + HLA DP, prediluted (FITC)
- Suitable for: Flow Cyt
- Reacts with: Human, Pig
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Product nameAnti-HLA DR + HLA DP antibody [HL-38], prediluted (FITC)
See all HLA DR + HLA DP primary antibodies
DescriptionMouse monoclonal [HL-38] to HLA DR + HLA DP, prediluted (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human, Pig
Burkitts lymphoma cell line Raji (Human).
EpitopeThis antibody recognizes a common epitope on the beta chain of human HLA DR and HLA DP.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituents: PBS, BSA
Concentration information loading...
Our Abpromise guarantee covers the use of ab18232 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHuman MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Cellular localizationCell Membrane; Single pass type I membrane protein
- HLA DP antibody
- HLA DR antibody
- MHC Class II antibody
ab18232 has been referenced in 1 publication.
- Do HV et al. Characterization of Insulin-Secreting Porcine Bone Marrow Stromal Cells Ex Vivo and Autologous Cell Therapy In Vivo. Cell Transplant 24:1205-20 (2015). PubMed: 24667101