Alexa Fluor® 488 Anti-HLA G antibody [87G] (ab187576)
Key features and details
- Alexa Fluor® 488 Mouse monoclonal [87G] to HLA G
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
- Isotype: IgG2a
Overview
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Product name
Alexa Fluor® 488 Anti-HLA G antibody [87G]
See all HLA G primary antibodies -
Description
Alexa Fluor® 488 Mouse monoclonal [87G] to HLA G -
Host species
Mouse -
Conjugation
Alexa Fluor® 488. Ex: 495nm, Em: 519nm -
Specificity
ab187576 recognizes both membrane-bound and soluble forms of HLA G (HLA G1 and HLA G5). ab187576 blocks interaction of HLA G with inhibitory receptors. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human
Predicted to work with: ChimpanzeeDoes not react with: Mouse, Rat -
Immunogen
Tissue, cells or virus corresponding to Human HLA G aa 1 to the C-terminus. HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA G and Human beta 2 Microglobulin.
Database link: P17693 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 8
Preservative: 0.097% Sodium azide
Constituents: 99% Tris buffered saline, 0.2% BSA -
Concentration information loading...
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Purity
Size exclusion -
Purification notes
ab187576 is conjugated with Alexa Fluor® 488 under optimum conditions. The conjugate is purified by size-exclusion chromatography. -
Clonality
Monoclonal -
Clone number
87G -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187576 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab171464 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. ab171464 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Target
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Function
Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells. -
Tissue specificity
Expressed in trophoblasts. -
Sequence similarities
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 449597 Chimpanzee
- Entrez Gene: 3135 Human
- Omim: 142871 Human
- SwissProt: Q95IT1 Chimpanzee
- SwissProt: P17693 Human
- Unigene: 512152 Human
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Alternative names
- B2 microglobulin antibody
- DADB-15K14.8 antibody
- HLA 6.0 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab187576 has not yet been referenced specifically in any publications.