Publishing research using ab18256? Please let us know so that we can cite the reference in this datasheet.

ab18256 has been referenced in 246 publications.

  • Ma F  et al. Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain. Neurosci Lett 699:54-58 (2019). PubMed: 30708129
  • Carr DF  et al. Serum and blister-fluid elevation and decreased epidermal content of high-mobility group box 1 protein in drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. Br J Dermatol N/A:N/A (2019). PubMed: 30613954
  • Bauzon M  et al. Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells. Oncoimmunology 8:e1565859 (2019). PubMed: 30906660
  • Geoghegan G  et al. Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism. Mol Metab 24:44-63 (2019). PubMed: 30948248
  • Honda T  et al. Acute and chronic remote ischemic conditioning attenuate septic cardiomyopathy, improve cardiac output, protect systemic organs, and improve mortality in a lipopolysaccharide-induced sepsis model. Basic Res Cardiol 114:15 (2019). PubMed: 30838474
  • Tsverava L  et al. Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis. Biomed Res Int 2019:4518160 (2019). PubMed: 30941363
  • Kim SJ  et al. GRSF1 is an age-related regulator of senescence. Sci Rep 9:5546 (2019). PubMed: 30944385
  • Kim SJ  et al. Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model. Lab Invest N/A:N/A (2019). PubMed: 31043679
  • Rogers C  et al. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun 10:1689 (2019). PubMed: 30976076
  • Warner SG  et al. A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression. Mol Ther Oncolytics 13:82-92 (2019). PubMed: 31061881
  • Kwak MS  et al. Peroxiredoxin-mediated disulfide bond formation is required for nucleocytoplasmic translocation and secretion of HMGB1 in response to inflammatory stimuli. Redox Biol 24:101203 (2019). PubMed: 31026770
  • Kim JE & Kang TC Differential Roles of Mitochondrial Translocation of Active Caspase-3 and HMGB1 in Neuronal Death Induced by Status Epilepticus. Front Cell Neurosci 12:301 (2018). PubMed: 30233331
  • Frank MG  et al. Stress disinhibits microglia via down-regulation of CD200R: A mechanism of neuroinflammatory priming. Brain Behav Immun 69:62-73 (2018). PubMed: 29104062
  • Zhang H  et al. Vitamin D reduces inflammatory response in asthmatic mice through HMGB1/TLR4/NF-?B signaling pathway. Mol Med Rep 17:2915-2920 (2018). PubMed: 29257249
  • Dyer MR  et al. Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA. Sci Rep 8:2068 (2018). PubMed: 29391442
  • de Vasconcelos NM  et al. Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture. Cell Death Differ N/A:N/A (2018). PubMed: 29666477
  • Wu K  et al. TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells. Mol Med Rep 18:3411-3420 (2018). PubMed: 30066873
  • Chen T  et al. Inhibiting of RIPK3 attenuates early brain injury following subarachnoid hemorrhage: Possibly through alleviating necroptosis. Biomed Pharmacother 107:563-570 (2018). PubMed: 30114640
  • Ovadya Y  et al. Impaired immune surveillance accelerates accumulation of senescent cells and aging. Nat Commun 9:5435 (2018). PubMed: 30575733
  • Tang Y  et al. Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-?B pathway. Am J Transl Res 10:4141-4151 (2018). PubMed: 30662657
  • Cheng Y  et al. TNFa disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice. Brain Behav Immun 69:556-567 (2018). WB . PubMed: 29452218
  • Shi Y  et al. HMGB1 mediates microglia activation via the TLR4/NF-?B pathway in coriaria lactone induced epilepsy. Mol Med Rep 17:5125-5131 (2018). PubMed: 29393419
  • Sprague L  et al. High Mobility Group Box 1 Influences HSV1716 Spread and Acts as an Adjuvant to Chemotherapy. Viruses 10:N/A (2018). PubMed: 29543735
  • Yun J  et al. Local S100A8 Levels Correlate With Recurrence of Experimental Autoimmune Uveitis and Promote Pathogenic T Cell Activity. Invest Ophthalmol Vis Sci 59:1332-1342 (2018). WB, ELISA ; Rat . PubMed: 29625456
  • Coleman LG  et al. HMGB1/IL-1ß complexes in plasma microvesicles modulate immune responses to burn injury. PLoS One 13:e0195335 (2018). PubMed: 29601597
  • Almeida R  et al. Chromatin conformation regulates the coordination between DNA replication and transcription. Nat Commun 9:1590 (2018). PubMed: 29686321
  • Kim SY  et al. High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation. Front Immunol 9:705 (2018). PubMed: 29696019
  • O'Leary MP  et al. Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose. J Transl Med 16:110 (2018). PubMed: 29699566
  • Barreiro-Alonso A  et al. Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer. Oncotarget 9:19050-19064 (2018). PubMed: 29721183
  • An K  et al. Spinal PKC activation - Induced neuronal HMGB1 translocation contributes to hyperalgesia in a bone cancer pain model in rats. Exp Neurol 303:80-94 (2018). WB . PubMed: 29428215
  • Chen X  et al. Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice. Sci Rep 8:8319 (2018). PubMed: 29844451
  • Liu X  et al. Paeonol attenuates acute lung injury by inhibiting HMGB1 in lipopolysaccharide-induced shock rats. Int Immunopharmacol 61:169-177 (2018). WB . PubMed: 29883962
  • Xie X  et al. MCPIP1-induced autophagy mediates ischemia/reperfusion injury in endothelial cells via HMGB1 and CaSR. Sci Rep 8:1735 (2018). PubMed: 29379093
  • Chinta SJ  et al. Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease. Cell Rep 22:930-940 (2018). PubMed: 29386135
  • Liu QY  et al. Inflammation responses in patients with pulmonary tuberculosis in an intensive care unit. Exp Ther Med 15:2719-2726 (2018). PubMed: 29456674
  • Collett GP  et al. Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules. Oncotarget 9:6707-6717 (2018). PubMed: 29467921
  • Cho E  et al. Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer. Oncotarget 9:7902-7917 (2018). PubMed: 29487701
  • Chu LH  et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun 9:996 (2018). PubMed: 29520027
  • Zhang J  et al. High mobility group box 1 promotes the epithelial-to-mesenchymal transition in prostate cancer PC3 cells via the RAGE/NF-?B signaling pathway. Int J Oncol 53:659-671 (2018). PubMed: 29845254
  • O'Leary MP  et al. A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection. Mol Ther Oncolytics 9:13-21 (2018). PubMed: 29988502
  • Shi Y  et al. DNA binding protein HMGB1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with OSA. Brain Behav Immun 73:482-492 (2018). PubMed: 29920330
  • Coleman LG  et al. HMGB1/IL-1ß complexes regulate neuroimmune responses in alcoholism. Brain Behav Immun 72:61-77 (2018). PubMed: 29102800
  • Cecchinato V  et al. Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis. Front Immunol 9:2118 (2018). PubMed: 30283452
  • Kim YH  et al. Inflachromene inhibits autophagy through modulation of Beclin 1 activity. J Cell Sci 131:N/A (2018). PubMed: 29361549
  • Ginno PA  et al. Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape. Nat Commun 9:4048 (2018). PubMed: 30279501
  • Murai S  et al. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nat Commun 9:4457 (2018). PubMed: 30367066
  • Huang M  et al. Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway. Int J Oncol 53:1481-1492 (2018). PubMed: 30066846
  • Liu W  et al. Ulinastatin protects the lungs of COPD rats through the HMGB1/TLR4 signaling pathway. Oncol Lett 16:4057-4063 (2018). PubMed: 30128028
  • Raby AC  et al. Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis. J Am Soc Nephrol 28:461-478 (2017). PubMed: 27432741
  • Nygaard U  et al. The "Alarmins" HMBG1 and IL-33 Downregulate Structural Skin Barrier Proteins and Impair Epidermal Growth. Acta Derm Venereol 97:305-312 (2017). PubMed: 27868148
  • Zhou X  et al. RIP3 attenuates the pancreatic damage induced by deletion of ATG7. Cell Death Dis 8:e2918 (2017). PubMed: 28703808
  • Osbourn M  et al. HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33. Immunity 47:739-751.e5 (2017). Mouse . PubMed: 29045903
  • Seo J  et al. A microengineered model of RBC transfusion-induced pulmonary vascular injury. Sci Rep 7:3413 (2017). PubMed: 28611413
  • Jeon OH  et al. Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment. Nat Med 23:775-781 (2017). IHC-P ; Mouse . PubMed: 28436958
  • Luan X  et al. HMGB1 is negatively correlated with the development of endometrial carcinoma and prevents cancer cell invasion and metastasis by inhibiting the process of epithelial-to-mesenchymal transition. Onco Targets Ther 10:1389-1402 (2017). PubMed: 28424555
  • Walker LE  et al. Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy. J Clin Invest 127:2118-2132 (2017). PubMed: 28504645
  • Wang WK  et al. Ulinastatin attenuates diabetes-induced cardiac dysfunction by the inhibition of inflammation and apoptosis. Exp Ther Med 14:2497-2504 (2017). PubMed: 28962186
  • Li S  et al. MicroRNA-34a directly targets high-mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma. Exp Ther Med 14:5611-5618 (2017). PubMed: 29285100
  • Ma F  et al. Macrophage migration inhibitory factor mediates protease-activated receptor 4-induced bladder pain through urothelial high mobility group box 1. Physiol Rep 5:N/A (2017). PubMed: 29263120
  • Lu J  et al. Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression. Nat Commun 8:1811 (2017). PubMed: 29180759
  • Van Opdenbosch N  et al. Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4. Cell Rep 21:3427-3444 (2017). PubMed: 29262324
  • Sun L  et al. Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-?B signaling in an IL-6-dependent manner. J Neuroinflammation 14:231 (2017). PubMed: 29178911
  • Conos SA  et al. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner. Proc Natl Acad Sci U S A 114:E961-E969 (2017). PubMed: 28096356
  • D'Eliseo D  et al. Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells. Genes Cancer 8:426-437 (2017). PubMed: 28435516
  • Choi JY  et al. High-mobility group box-1 as an autocrine trophic factor in white matter stroke. Proc Natl Acad Sci U S A 114:E4987-E4995 (2017). PubMed: 28584116
  • Xie Y  et al. HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-?B signaling pathway. Mol Med Rep 16:1691-1700 (2017). PubMed: 28627626
  • Rong X  et al. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest 127:3640-3651 (2017). PubMed: 28846071
  • Nestvold J  et al. Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model. Oncoimmunology 6:e1338236 (2017). PubMed: 28920000
  • Cui YL  et al. Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome. Oncotarget 8:56980-56990 (2017). PubMed: 28915647
  • Chang J  et al. Cyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells. PLoS One 12:e0184770 (2017). WB . PubMed: 28898270
  • Holmes CJ  et al. Burn Injury Alters Epidermal Cholinergic Mediators and Increases HMGB1 and Caspase 3 in Autologous Donor Skin and Burn Margin. Shock 47:175-183 (2017). PubMed: 27648692
  • Laronda MM  et al. A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Nat Commun 8:15261 (2017). WB, IHC . PubMed: 28509899
  • Kim M  et al. GFRA1 promotes cisplatin-induced chemoresistance in osteosarcoma by inducing autophagy. Autophagy 13:149-168 (2017). PubMed: 27754745
  • Xia J  et al. Inhibiting the cytoplasmic location of HMGB1 reverses cisplatin resistance in human cervical cancer cells. Mol Med Rep 15:488-494 (2017). PubMed: 27959427
  • Guha M  et al. DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes. J Biol Chem 292:6542-6554 (2017). PubMed: 28242760
  • Lawrimore CJ & Crews FT Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2. Alcohol Clin Exp Res 41:939-954 (2017). PubMed: 28273337
  • Avgousti DC  et al. Adenovirus core protein VII down-regulates the DNA damage response on the host genome. J Virol N/A:N/A (2017). PubMed: 28794020
  • Kaneko Y  et al. Extracellular HMGB1 Modulates Glutamate Metabolism Associated with Kainic Acid-Induced Epilepsy-Like Hyperactivity in Primary Rat Neural Cells. Cell Physiol Biochem 41:947-959 (2017). PubMed: 28222432
  • Zhou X  et al. The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis. Cell Death Discov 3:17027 (2017). IF ; Human . PubMed: 28660075
  • Li Z  et al. Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma. Cell Death Dis 8:e2775 (2017). WB . PubMed: 28492546
  • Shen W  et al. High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4. Mol Med Rep 15:2530-2536 (2017). IHC-Fr ; Human . PubMed: 28260034
  • Pellegrini L  et al. HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. Oncotarget 8:22649-22661 (2017). PubMed: 28186988
  • Davis HM  et al. Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. Aging Cell 16:551-563 (2017). PubMed: 28317237
  • Jin JK  et al. ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Circ Res 120:862-875 (2017). PubMed: 27932512
  • Wang J  et al. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest 127:987-1004 (2017). PubMed: 28192372
  • Coleman LG  et al. Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7. J Neuroinflammation 14:22 (2017). PubMed: 28118842
  • Wen S  et al. Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury. J Cell Mol Med 21:432-443 (2017). IF . PubMed: 27677535
  • He J  et al. Expression of high mobility group box 1 protein predicts a poorer prognosis for patients with osteosarcoma. Oncol Lett 11:293-298 (2016). PubMed: 26870206
  • Hiraku Y  et al. Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation. Part Fibre Toxicol 13:16 (2016). PubMed: 27026438
  • Lundbäck P  et al. Characterization of the Inflammatory Properties of Actively Released HMGB1 in Juvenile Idiopathic Arthritis. Antioxid Redox Signal 24:605-19 (2016). PubMed: 25532033
  • Gdynia G  et al. The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764 (2016). WB . PubMed: 26948869
  • Park IA  et al. Endoplasmic reticulum stress induces secretion of high-mobility group proteins and is associated with tumor-infiltrating lymphocytes in triple-negative breast cancer. Oncotarget 7:59957-59964 (2016). IHC . PubMed: 27494867
  • Fujita K  et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep 6:31895 (2016). IHC, Electron Microscopy . PubMed: 27557632
  • Achouiti A  et al. Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia. PLoS One 11:e0141000 (2016). PubMed: 26824892
  • Avgousti DC  et al. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature 535:173-7 (2016). PubMed: 27362237
  • Zhao H  et al. Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response. Int J Mol Med 37:1014-22 (2016). WB . PubMed: 26935388
  • Hyun HW  et al. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci 10:99 (2016). PubMed: 27147971
  • Lin HJ  et al. Helicobacter pylori Activates HMGB1 Expression and Recruits RAGE into Lipid Rafts to Promote Inflammation in Gastric Epithelial Cells. Front Immunol 7:341 (2016). PubMed: 27667993
  • Qian X  et al. Expression of aldehyde dehydrogenase family 1 member A1 and high mobility group box 1 in oropharyngeal squamous cell carcinoma in association with survival time. Oncol Lett 12:3429-3434 (2016). IHC-P ; Human . PubMed: 27900016
  • Lee JH  et al. Hypothermia inhibits the propagation of acute ischemic injury by inhibiting HMGB1. Mol Brain 9:81 (2016). IHC-P ; Rat . PubMed: 27544687
  • Lai CH  et al. Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm. PLoS One 11:e0146565 (2016). PubMed: 26741694
  • Kouzoukas DE  et al. Protease-Activated Receptor 4 Induces Bladder Pain through High Mobility Group Box-1. PLoS One 11:e0152055 (2016). WB, IHC . PubMed: 27010488
  • Xiong X  et al. Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms. J Neuroinflammation 13:241 (2016). WB ; Rat . PubMed: 27609334
  • Jog NR  et al. Urinary high-mobility group box-1 associates specifically with lupus nephritis class V. Lupus 25:1551-1557 (2016). PubMed: 27075010
  • Hosakote YM  et al. Respiratory Syncytial Virus Infection Triggers Epithelial HMGB1 Release as a Damage-Associated Molecular Pattern Promoting a Monocytic Inflammatory Response. J Virol 90:9618-9631 (2016). PubMed: 27535058
  • Kim YH  et al. N-linked glycosylation plays a crucial role in the secretion of HMGB1. J Cell Sci 129:29-38 (2016). PubMed: 26567221
  • Takizawa T  et al. Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice. Cephalalgia 36:44-52 (2016). PubMed: 25862357
  • Cheng Y  et al. Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. Brain Behav Immun 53:207-222 (2016). PubMed: 26772151
  • Chen R  et al. Novel chemokine-like activities of histones in tumor metastasis. Oncotarget 7:61728-61740 (2016). PubMed: 27623211
  • Grootaert MOJ  et al. NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice. Atherosclerosis 252:166-174 (2016). PubMed: 27425215
  • Li Z  et al. Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death Differ 23:1428-47 (2016). PubMed: 26943325
  • Napolitano A  et al. HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. Clin Cancer Res 22:3087-96 (2016). PubMed: 26733616
  • Son SM  et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy 12:784-800 (2016). PubMed: 26963025
  • Ni HM  et al. Caspase Inhibition Prevents Tumor Necrosis Factor-a-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro. Am J Pathol 186:2623-36 (2016). PubMed: 27616656
  • Kim J  et al. The RAGE receptor and its ligands are highly expressed in astrocytes in a grade-dependant manner in the striatum and subependymal layer in Huntington's disease. J Neurochem 134:927-42 (2015). PubMed: 26011179
  • Burmeister DM  et al. Utility of spatial frequency domain imaging (SFDI) and laser speckle imaging (LSI) to non-invasively diagnose burn depth in a porcine model. Burns 41:1242-52 (2015). PubMed: 26138371
  • Vogel S  et al. Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest 125:4638-54 (2015). WB, IHC-Fr, ICC/IF ; Mouse . PubMed: 26551681
  • Aslani F  et al. Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis. Hum Reprod 30:417-31 (2015). PubMed: 25452436
  • Gustin A  et al. NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes. PLoS One 10:e0130624 (2015). ICC . PubMed: 26091541
  • Dembowski JA & DeLuca NA Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes. PLoS Pathog 11:e1004939 (2015). ICC/IF . PubMed: 26018390
  • Hasan M  et al. Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice. J Immunol 195:4573-7 (2015). PubMed: 26432890
  • Parodi M  et al. Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment. Oncoimmunology 4:e1052353 (2015). PubMed: 26587323
  • Ito H  et al. HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. EMBO Mol Med 7:78-101 (2015). WB, IHC . PubMed: 25510912
  • Huebener P  et al. The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis. J Clin Invest 125:539-50 (2015). PubMed: 25562324
  • Hasan M  et al. Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation. Immunity 43:463-74 (2015). PubMed: 26320659
  • Norouzitallab P  et al. Non-lethal heat shock induces HSP70 and HMGB1 protein production sequentially to protect Artemia franciscana against Vibrio campbellii. Fish Shellfish Immunol 42:395-9 (2015). PubMed: 25463291
  • Giordano C  et al. Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy. Hum Mol Genet 24:2147-62 (2015). IHC-Fr ; Mouse . PubMed: 25552658
  • Zhu X  et al. Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation. J Clin Invest 125:1098-110 (2015). PubMed: 25642769
  • Chen Y  et al. HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products. PLoS One 10:e0140918 (2015). WB, IHC . PubMed: 26485677
  • Liesz A  et al. DAMP signaling is a key pathway inducing immune modulation after brain injury. J Neurosci 35:583-98 (2015). PubMed: 25589753
  • Wang FC  et al. Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro. World J Gastroenterol 21:7764-76 (2015). PubMed: 26167076
  • Palmblad K  et al. High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome. Mol Med 20:538-47 (2015). PubMed: 25247290
  • Polanská E  et al. Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1. PLoS One 9:e89070 (2014). PubMed: 24551219
  • Rickard JA  et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157:1175-88 (2014). PubMed: 24813849
  • Marshall KD  et al. Proteomic mapping of proteins released during necrosis and apoptosis from cultured neonatal cardiac myocytes. Am J Physiol Cell Physiol 306:C639-47 (2014). PubMed: 24401845
  • Amornsupak K  et al. Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells. BMC Cancer 14:955 (2014). WB . PubMed: 25512109
  • Liu K  et al. MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell. Autophagy 10:442-52 (2014). PubMed: 24418846
  • Yang L  et al. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. Nat Commun 5:4436 (2014). WB ; Mouse . PubMed: 25019241
  • Kim JE  et al. LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission. Cell Death Differ : (2014). PubMed: 24561342
  • Abu El-Asrar AM  et al. The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes. Mediators Inflamm 2014:746415 (2014). WB . PubMed: 24733965
  • Xia M  et al. Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus. Oncotarget 5:3907-18 (2014). WB . PubMed: 25004098
  • Weber DJ  et al. The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation. Sci Transl Med 6:252ra124 (2014). PubMed: 25186179
  • Su Z  et al. Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCß/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1. J Cell Mol Med 18:1740-51 (2014). ICC/IF ; Mouse . PubMed: 24912759
  • Ebrahimkhani MR  et al. Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney. Proc Natl Acad Sci U S A 111:E4878-86 (2014). PubMed: 25349415
  • Xu H  et al. High mobility group box 1 release from cholangiocytes in patients with acute-on-chronic liver failure. Exp Ther Med 8:1178-1184 (2014). IHC ; Human . PubMed: 25187820
  • Tomasella A  et al. A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1. J Biol Chem 289:25699-710 (2014). Human . PubMed: 25096578
  • Peeters PM  et al. Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs. Part Fibre Toxicol 11:58 (2014). ELISA, IHC-P ; Human . PubMed: 25406505
  • Yang PS  et al. Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats. Respir Res 15:148 (2014). ELISA, IHC-Fr ; Rat . PubMed: 25420924
  • Johansson L  et al. HMGB1 in severe soft tissue infections caused by Streptococcus pyogenes. Front Cell Infect Microbiol 4:4 (2014). IHC-Fr ; Human . PubMed: 24524027
  • Santos AR  et al. Cellular mechanisms of high mobility group 1 (HMGB-1) protein action in the diabetic retinopathy. PLoS One 9:e87574 (2014). WB ; Mouse . PubMed: 24498140
  • Lu B  et al. JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. Proc Natl Acad Sci U S A 111:3068-73 (2014). IP ; Mouse . PubMed: 24469805
  • Van Opdenbosch N  et al. Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun 5:3209 (2014). WB ; Mouse . PubMed: 24492532
  • Parasa VR  et al. Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue. Dis Model Mech 7:281-8 (2014). IHC-Fr ; Human . PubMed: 24203885
  • Zou JY & Crews FT Release of neuronal HMGB1 by Ethanol through decreased HDAC activity activates brain neuroimmune signaling. PLoS One 9:e87915 (2014). WB ; Human . PubMed: 24551070
  • Nogueira AV  et al. HMGB1 localization during experimental periodontitis. Mediators Inflamm 2014:816320 (2014). WB ; Mouse, Rat . PubMed: 24692854
  • Gong G  et al. Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats. PLoS One 9:e89450 (2014). WB, IHC-FoFr ; Rat . PubMed: 24594628
  • Miller JM  et al. Curcumin: a double hit on malignant mesothelioma. Cancer Prev Res (Phila) 7:330-40 (2014). PubMed: 24431405
  • Qiu Y  et al. HMGB1-promoted and TLR2/4-dependent NK cell maturation and activation take part in rotavirus-induced murine biliary atresia. PLoS Pathog 10:e1004011 (2014). IF ; Mouse . PubMed: 24651485
  • Kuroda N  et al. Apoptotic response through a high mobility box 1 protein-dependent mechanism in LPS/GalN-induced mouse liver failure and glycyrrhizin-mediated inhibition. PLoS One 9:e92884 (2014). IHC-P, ChIP ; Mouse . PubMed: 24690901
  • Zhu Z  et al. Haploinsufficiency of Def Activates p53-Dependent TGFß Signalling and Causes Scar Formation after Partial Hepatectomy. PLoS One 9:e96576 (2014). WB, ICC/IF ; Zebrafish . PubMed: 24801718
  • Zhao C  et al. Nuclear Factor E2-related Factor-2 (Nrf2) Is Required for NLRP3 and AIM2 Inflammasome Activation. J Biol Chem 289:17020-17029 (2014). WB . PubMed: 24798340
  • Choy M  et al. A novel, noninvasive, predictive epilepsy biomarker with clinical potential. J Neurosci 34:8672-84 (2014). PubMed: 24966369
  • Müller MC  et al. Contribution of damage-associated molecular patterns to transfusion-related acute lung injury in cardiac surgery. Blood Transfus 12:368-75 (2014). WB ; Human . PubMed: 24887223
  • Ge X  et al. High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD). J Biol Chem 289:22672-91 (2014). IHC-P ; Human . PubMed: 24928512
  • Laird MD  et al. High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4. Glia 62:26-38 (2014). PubMed: 24166800
  • Abe A  et al. High Mobility Group Box1 (HMGB1) released from cancer cells induces the expression of pro-inflammatory cytokines in peritoneal fibroblasts. Pathol Int 64:267-75 (2014). PubMed: 24965109
  • Pavlosky A  et al. RIPK3-mediated necroptosis regulates cardiac allograft rejection. Am J Transplant 14:1778-90 (2014). PubMed: 24984764
  • De Toma I  et al. Nucleosome loss facilitates the chemotactic response of macrophages. J Intern Med 276:454-69 (2014). PubMed: 25069756
  • Yang M  et al. Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis. Biochem Pharmacol 86:410-8 (2013). PubMed: 23707973
  • Achouiti A  et al. Limited role of the receptor for advanced glycation end products during Streptococcus pneumoniae bacteremia. J Innate Immun 5:603-12 (2013). PubMed: 23774862
  • Gu L  et al. T cells contribute to stroke-induced lymphopenia in rats. PLoS One 8:e59602 (2013). WB ; Rat . PubMed: 23555048
  • Crnogorac-Jurcevic T  et al. Molecular analysis of precursor lesions in familial pancreatic cancer. PLoS One 8:e54830 (2013). IHC-P ; Human . PubMed: 23372777
  • Melis MH  et al. Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response. Cell Death Differ 20:765-73 (2013). Mouse . PubMed: 23412345
  • Simpson KL  et al. A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers. Cell Death Dis 4:e613 (2013). WB, ELISA, IHC-P ; Mouse, Human . PubMed: 23640455
  • Fang H  et al. Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase. Cell Death Dis 4:e694 (2013). PubMed: 23807223
  • Lippai D  et al. Alcohol-induced IL-1ß in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. J Leukoc Biol 94:171-82 (2013). PubMed: 23625200
  • Lee Y  et al. Clinical significance of serum high-mobility group box 1 level in alopecia areata. J Am Acad Dermatol 69:742-7 (2013). PubMed: 23932647
  • Hillegass JM  et al. Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells. Part Fibre Toxicol 10:39 (2013). WB ; Human . PubMed: 23937860
  • Vu K  et al. Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cells. Infect Immun 81:3139-47 (2013). PubMed: 23774597
  • Whilding LM  et al. Vaccinia virus induces programmed necrosis in ovarian cancer cells. Mol Ther 21:2074-86 (2013). WB . PubMed: 23985697
  • Niedelman W  et al. Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication. Infect Immun 81:4341-9 (2013). Human . PubMed: 24042117
  • Roundy LM  et al. LL-37 induced cystitis and the receptor for advanced glycation end-products (RAGE) pathway. Adv Biosci Biotechnol 4:1-8 (2013). PubMed: 24883227
  • Yan HX  et al. p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release. J Hepatol 59:762-8 (2013). PubMed: 23714159
  • Qiang X  et al. Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nat Med 19:1489-1495 (2013). WB . PubMed: 24097189
  • Hasan M  et al. Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes. Nat Immunol 14:61-71 (2013). PubMed: 23160154
  • D'Eliseo D  et al. Capsaicin as an inducer of damage-associated molecular patterns (DAMPs) of immunogenic cell death (ICD) in human bladder cancer cells. Cell Stress Chaperones 18:801-8 (2013). PubMed: 23580156
  • Nyström S  et al. TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis. EMBO J 32:86-99 (2013). PubMed: 23222484
  • Peeters PM  et al. Silica induces NLRP3 inflammasome activation in human lung epithelial cells. Part Fibre Toxicol 10:3 (2013). ELISA . PubMed: 23402370
  • Rangel R  et al. Targeting mammalian organelles with internalizing phage (iPhage) libraries. Nat Protoc 8:1916-39 (2013). PubMed: 24030441
  • Abu El-Asrar AM  et al. High-mobility group box-1 induces decreased brain-derived neurotrophic factor-mediated neuroprotection in the diabetic retina. Mediators Inflamm 2013:863036 (2013). WB . PubMed: 23766563
  • Kang R  et al. Autophagy is required for IL-2-mediated fibroblast growth. Exp Cell Res 319:556-65 (2013). PubMed: 23195496
  • Juranek JK  et al. Increased expression of the receptor for advanced glycation end-products in human peripheral neuropathies. Brain Behav 3:701-9 (2013). IF . PubMed: 24363972
  • Moisy D  et al. HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication. J Virol 86:9122-33 (2012). PubMed: 22696656
  • Yang H  et al. Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med 18:250-9 (2012). PubMed: 22105604
  • Zhai CL  et al. Glycyrrhizin protects rat heart against ischemia-reperfusion injury through blockade of HMGB1-dependent phospho-JNK/Bax pathway. Acta Pharmacol Sin : (2012). WB . PubMed: 23064724
  • Pierce A  et al. Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation. PLoS One 7:e38928 (2012). WB . PubMed: 22745689
  • Franklin S  et al. Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol Cell Proteomics : (2012). WB . PubMed: 22270000
  • Rabadi MM  et al. Interaction between uric acid and HMGB1 translocation and release from endothelial cells. Am J Physiol Renal Physiol 302:F730-41 (2012). WB ; Human . PubMed: 22189943
  • Kouzaki H  et al. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol 186:4375-87 (2011). PubMed: 21357533
  • Wang HL  et al. The inhibitory effect of lidocaine on the release of high mobility group box 1 in lipopolysaccharide-stimulated macrophages. Anesth Analg 112:839-44 (2011). PubMed: 21288974
  • Zurolo E  et al. Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development. Brain 134:1015-32 (2011). PubMed: 21414994
  • Li J  et al. Neutralization of the extracellular HMGB1 released by ischaemic damaged renal cells protects against renal ischaemia-reperfusion injury. Nephrol Dial Transplant 26:469-78 (2011). IHC-P ; Mouse . PubMed: 20679140
  • Xu H  et al. Endogenous HMGB1 contributes to ischemia-reperfusion-induced myocardial apoptosis by potentiating the effect of TNF-α/JNK. Am J Physiol Heart Circ Physiol 300:H913-21 (2011). PubMed: 21186276
  • Guerriero JL  et al. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol 186:3517-26 (2011). WB ; Mouse . PubMed: 21300822
  • Chase GP  et al. Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting. PLoS Pathog 7:e1002187 (2011). PubMed: 21909257
  • Liu Z  et al. Knockdown of HMGB1 in tumor cells attenuates their ability to induce regulatory T cells and uncovers naturally acquired CD8 T cell-dependent antitumor immunity. J Immunol 187:118-25 (2011). PubMed: 21642542
  • Dvoriantchikova G  et al. The high-mobility group box-1 nuclear factor mediates retinal injury after ischemia reperfusion. Invest Ophthalmol Vis Sci 52:7187-94 (2011). PubMed: 21828158
  • Peters LR & Raghavan M Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cells. J Immunol 187:919-31 (2011). PubMed: 21670312
  • Raby AC  et al. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. Eur J Immunol 41:2741-52 (2011). WB . PubMed: 21630250
  • Tang H  et al. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol 185:2563-9 (2010). PubMed: 20631308
  • Peña G  et al. JAK2 inhibition prevents innate immune responses and rescues animals from sepsis. J Mol Med (Berl) 88:851-9 (2010). PubMed: 20393690
  • Evankovich J  et al. High Mobility Group Box 1 Release from Hepatocytes during Ischemia and Reperfusion Injury Is Mediated by Decreased Histone Deacetylase Activity. J Biol Chem 285:39888-97 (2010). PubMed: 20937823
  • Wang L  et al. Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression. Neurosci Lett 471:152-6 (2010). WB, IHC-FoFr ; Rat . PubMed: 20100543
  • Ferhani N  et al. Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in COPD. Am J Respir Crit Care Med : (2010). PubMed: 20133931
  • Yu H  et al. Role of high-mobility group box 1 protein and poly(ADP-ribose) polymerase 1 degradation in Chlamydia trachomatis-induced cytopathicity. Infect Immun 78:3288-97 (2010). WB, ELISA ; Human . PubMed: 20421386
  • Ramos L  et al. Mast cell stabilization improves survival by preventing apoptosis in sepsis. J Immunol 185:709-16 (2010). ELISA ; Mouse . PubMed: 20519642
  • Mittal D  et al. TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. EMBO J 29:2242-52 (2010). IHC-P ; Mouse . PubMed: 20526283
  • Lamkanfi M  et al. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J Immunol 185:4385-92 (2010). ICC/IF ; Mouse . PubMed: 20802146
  • Xu H  et al. The alarmin cytokine, high mobility group box 1, is produced by viable cardiomyocytes and mediates the lipopolysaccharide-induced myocardial dysfunction via a TLR4/phosphatidylinositol 3-kinase gamma pathway. J Immunol 184:1492-8 (2010). WB, ELISA, IHC-Fr ; Mouse . PubMed: 20028656
  • Tesniere A  et al. Immunogenic death of colon cancer cells treated with oxaliplatin. Oncogene 29:482-91 (2010). ICC/IF . PubMed: 19881547
  • Chalmin F  et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest 120:457-71 (2010). WB . PubMed: 20093776
  • Peng RQ  et al. Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer. BMC Cancer 10:496 (2010). PubMed: 20846416
  • Laserna EJ  et al. Proteomic analysis of phosphorylated nuclear proteins underscores novel roles for rapid actions of retinoic acid in the regulation of mRNA splicing and translation. Mol Endocrinol 23:1799-814 (2009). PubMed: 19812389
  • Leemans JC  et al. The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury. PLoS One 4:e5704 (2009). IHC-P ; Mouse . PubMed: 19479087
  • Cayrol C & Girard JP The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci U S A 106:9021-6 (2009). WB ; Human . PubMed: 19439663
  • Ito H  et al. Knock-down of PQBP1 impairs anxiety-related cognition in mouse. Hum Mol Genet 18:4239-54 (2009). WB ; Mouse . PubMed: 19661183
  • Yanai H  et al. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462:99-103 (2009). WB ; Mouse . PubMed: 19890330
  • Liu H  et al. Elevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis. Mol Cancer Res 7:1099-109 (2009). PubMed: 19584263
  • Krynetskaia NF  et al. Chromatin-associated proteins HMGB1/2 and PDIA3 trigger cellular response to chemotherapy-induced DNA damage. Mol Cancer Ther 8:864-72 (2009). WB ; Human . PubMed: 19372559
  • Craven RR  et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One 4:e7446 (2009). WB . PubMed: 19826485
  • Azad MB  et al. Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy 4:195-204 (2008). PubMed: 18059169
  • Youn JH  et al. High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-{alpha} Production in Human Monocytes. J Immunol 180:5067-74 (2008). ELISA ; Human . PubMed: 18354232
  • García-Escudero V  et al. Glioma regression in vitro and in vivo by a suicide combined treatment. Mol Cancer Res 6:407-17 (2008). PubMed: 18337448
  • Rittirsch D  et al. Functional roles for C5a receptors in sepsis. Nat Med 14:551-7 (2008). PubMed: 18454156
  • Andrassy M  et al. High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation 117:3216-26 (2008). PubMed: 18574060
  • Apetoh L  et al. Immunogenicity of anthracyclines: moving towards more personalized medicine. Trends Mol Med 14:141-51 (2008). PubMed: 18353726
  • Da Silva CA  et al. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol 181:4279-86 (2008). ELISA . PubMed: 18768886
  • Zhang X  et al. Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages. J Immunol 181:5015-23 (2008). WB, ICC/IF ; Mouse . PubMed: 18802105
  • Kappes F  et al. DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress. Mol Cell Biol 28:3245-57 (2008). WB ; Human . PubMed: 18332104
  • Thorburn J  et al. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ : (2008). PubMed: 18846108
  • Rowe SM  et al. Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med 178:822-31 (2008). PubMed: 18658107
  • Brusa D  et al. Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity. Vaccine 26:6422-32 (2008). WB ; Human . PubMed: 18848858
  • Heo K  et al. Isolation and characterization of proteins associated with histone H3 tails in vivo. J Biol Chem 282:15476-83 (2007). PubMed: 17403666
  • Wu H  et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 117:2847-59 (2007). IHC-P ; Mouse . PubMed: 17853945
  • Tracy K  et al. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol 27:6229-42 (2007). ICC/IF ; Mouse . PubMed: 17576813
  • Wu X  et al. Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways. Oxid Med Cell Longev 2016:1015390 (0). WB, IHC . PubMed: 27688824

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up