Overview

  • Product name

    Anti-HMGCR (phospho S872) antibody
    See all HMGCR primary antibodies
  • Description

    Rabbit polyclonal to HMGCR (phospho S872)
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human HMGCR aa 840-888 (C terminal) (phospho S871) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P04035

  • Positive control

    • IHC-P: Rat liver tissue; Mouse brain and intestine tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab215437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.
  • Pathway

    Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.
  • Sequence similarities

    Belongs to the HMG-CoA reductase family.
  • Cellular localization

    Endoplasmic reticulum membrane. Peroxisome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 3 hydroxy 3 methylglutaryl CoA reductase antibody
    • 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody
    • 3 hydroxymethylglutaryl CoA reductase antibody
    • 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody
    • 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody
    • 3H3M antibody
    • HMDH_HUMAN antibody
    • HMG CoA reductase antibody
    • HMG CoAR antibody
    • HMG-CoA reductase antibody
    • Hmgcr antibody
    • Hydroxymethylglutaryl CoA reductase antibody
    • LDLCQ3 antibody
    • MGC103269 antibody
    • Red antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded mouse intestine tissue stained for HMGCR using ab215437 at 1/200 dilution in immunohistochemical analysis. Detection: DAB staining.

  • Formalin-fixed, paraffin-embedded mouse brain tissue stained for HMGCR using ab215437 at 1/200 dilution in immunohistochemical analysis. Detection: DAB staining.

  • Formalin-fixed, paraffin-embedded rat liver tissue stained for HMGCR using ab215437 at 1/200 dilution in immunohistochemical analysis. Detection: DAB staining.

References

ab215437 has not yet been referenced specifically in any publications.

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