Overview

  • Product name

  • Description

    Rabbit polyclonal to HMIC
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human HMIC aa 485-498.
    Sequence:

    CHESYARSDTKLGP


    Database link: Q9NR34

  • Positive control

    • Lysate of HEK293T cells overexpressing HMIC; rat liver whole extract.
  • General notes

    Previously labelled as MAN1C1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab214768 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 10 µg/ml. Predicted molecular weight: 71 kDa.

Target

  • Relevance

    HMIC belongs to the glycosyl hydrolase 47 family. It is involved in the maturation of Asn-linked oligosaccharides. It trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. HMIC is expressed in most tissues with the exception of lung, muscle and pancreas. It is highly expressed in placenta.
  • Cellular localization

    Golgi apparatus membrane; Single-pass type II membrane protein.
  • Database links

  • Alternative names

    • 1 2 alpha mannosidase IC antibody
    • Alpha 1 2 mannosidase IC antibody
    • HMIC antibody
    • MAN1A3 antibody
    • MAN1C antibody
    • MAN1C1 antibody
    • Mannosidase alpha class 1C member 1 antibody
    • Mannosyl oligosaccharide 1 2 alpha mannosidase IC antibody
    • pp6318 antibody
    • Processing alpha 1 2 mannosidase IC antibody
    see all

Images

  • Lanes 1-2 : Anti-HMIC antibody (ab214768) at 5 µg/ml
    Lane 3 : Anti-HMIC antibody (ab214768) at 10 µg/ml

    Lanes 1 & 3 : rat liver whole extract
    Lane 2 : rat liver whole extract with Human HMIC immunizing peptide (485-498 aa)

    Secondary
    All lanes : goat anti-rabbit IgG peroxidase-conjugated

    Developed using the ECL technique.

    Predicted band size: 71 kDa

  • Lane 1 : Anti-HMIC antibody (ab214768) at 0.1 µg/ml
    Lanes 2-3 : Anti-HMIC antibody (ab214768) at 0.2 µg/ml

    Lanes 1-2 : Lysate of HEK293T cells overexpressing HMIC
    Lane 3 : Lysate of HEK293T cells overexpressing HMIC with Human HMIC immunizing peptide (485-498 aa)

    Secondary
    All lanes : goat anti-rabbit IgG peroxidase-conjugated

    Developed using the ECL technique.

    Predicted band size: 71 kDa

References

ab214768 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab214768.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up