Overview

  • Product name
    Anti-HNK-1ST antibody - Conformation-Specific
    See all HNK-1ST primary antibodies
  • Description
    Rabbit polyclonal to HNK-1ST - Conformation-Specific
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human HNK-1ST aa 207-236 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: O43529

  • Positive control
    • HL-60 cell line lysate
  • General notes

    Previously labelled as CHST10.

Properties

Applications

Our Abpromise guarantee covers the use of ab173123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

Target

  • Function
    Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
  • Tissue specificity
    In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.
  • Sequence similarities
    Belongs to the sulfotransferase 2 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carbohydrate sulfotransferase 10 antibody
    • CHST10 antibody
    • CHSTA_HUMAN antibody
    • EC 2.8.2.- antibody
    • HNK-1 sulfotransferase antibody
    • HNK-1ST antibody
    • HNK1ST antibody
    • huHNK-1ST antibody
    • MGC17148 antibody
    • OTTHUMP00000203188 antibody
    see all

Images

  • Anti-HNK-1ST antibody - Conformation-Specific (ab173123) at 1/100 dilution + HL-60 cell line lysate at 35 µg

    Predicted band size: 42 kDa

References

ab173123 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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