Key features and details
- Insulin receptor tyrosine kinase inhibitor
- CAS Number: 120944-03-8
- Purity: > 98%
- Soluble in ethanol to 25 mM and in DMSO to 25mM
- Form / State: Solid
- Source: Synthetic
Product nameHNMPA-(AM)3, Insulin receptor tyrosine kinase inhibitor
DescriptionInsulin receptor tyrosine kinase inhibitor
Biological descriptionInsulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Cell-permeable analog of HNMPA (cell impermeable analog available ab141566).
Product's appearance is colorless oil
Chemical nameP-[[(Acetyloxy)methoxy]-2-naphthalenylmethyl]-bis[(acetyloxy)methyl] ester phosphonic acid
Storage instructionsShipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 25 mM and in DMSO to 25mM
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141567 has been referenced in 1 publication.
- Norouzi S et al. Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines. PLoS One 13:e0191727 (2018). PubMed: 29373583