Overview

  • Product name

    Anti-hnRNP F antibody [3H4]
    See all hnRNP F primary antibodies
  • Description

    Mouse monoclonal [3H4] to hnRNP F
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length hnRNPF protein (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab6095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
ELISA Use at an assay dependent concentration.

Target

  • Function

    Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
  • Tissue specificity

    Expressed ubiquitously.
  • Sequence similarities

    Contains 3 RRM (RNA recognition motif) domains.
  • Domain

    The N-terminal RRM domains are responsible for recognizing the G-tract of BCL-X RNA.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
    Sumoylated.
  • Cellular localization

    Nucleus > nucleoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Heterogeneous nuclear ribonucleoprotein F antibody
    • hnRNP F antibody
    • HnRNP F protein antibody
    • Hnrnpf antibody
    • HNRPF antibody
    • HNRPF_HUMAN antibody
    • mcs94 1 antibody
    • MGC110997 antibody
    • N-terminally processed antibody
    • Nucleolin like protein antibody
    • Nucleolin like protein mcs94 1 antibody
    • Nucleolin-like protein mcs94-1 antibody
    • OK/SW-cl.23 antibody
    • OTTHUMP00000019482 antibody
    • OTTHUMP00000043413 antibody
    • OTTHUMP00000043414 antibody
    • Ribonucleoprotein F antibody
    see all

References

This product has been referenced in:

  • Balasubramani M  et al. Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer. Cancer Res 66:763-9 (2006). WB ; Human . Read more (PubMed: 16424007) »
See 1 Publication for this product

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