Product namehnRNP F peptide
See all hnRNP F proteins and peptides
Our Abpromise guarantee covers the use of ab197136 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
- Heterogeneous nuclear ribonucleoprotein F
- hnRNP F
- HnRNP F protein
FunctionComponent of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Tissue specificityExpressed ubiquitously.
Sequence similaritiesContains 3 RRM (RNA recognition motif) domains.
DomainThe N-terminal RRM domains are responsible for recognizing the G-tract of BCL-X RNA.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationNucleus > nucleoplasm.
- Information by UniProt
ab197136 has not yet been referenced specifically in any publications.