Key features and details
- Rabbit polyclonal to HO-2
- Suitable for: WB, IP, IHC-Fr
- Reacts with: Mouse, Rat, Hamster, Human, Monkey
- Isotype: IgG
Product nameAnti-HO-2 antibody
See all HO-2 primary antibodies
DescriptionRabbit polyclonal to HO-2
Tested applicationsSuitable for: WB, IP, IHC-Frmore details
Species reactivityReacts with: Mouse, Rat, Hamster, Human, Monkey
Synthetic peptide corresponding to Human HO-2. Sequence surrounding amino acid 25
- rat microsomes
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab24534 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 36 kDa.|
|IP||Use a concentration of 20 µg/ml.|
|IHC-Fr||Use a concentration of 20 µg/ml.|
FunctionHeme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Sequence similaritiesBelongs to the heme oxygenase family.
Contains 2 HRM (heme regulatory motif) repeats.
Cellular localizationMicrosome. Endoplasmic reticulum.
- Information by UniProt
- Heme oxygenase (decycling) 2 antibody
- Heme oxygenase (decyclizing) 2 antibody
- Heme oxygenase 2 antibody
ab24534 has been referenced in 1 publication.
- Potrykus J et al. Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events. PLoS Pathog 9:e1003676 (2013). IHC-Fr ; Mouse . PubMed: 24146619