Overview

  • Product name

    Anti-HOMER3 antibody
  • Description

    Rabbit polyclonal to HOMER3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 55 and 275 of HOMER3 (AAH12113).

  • Positive control

    • NT2D1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab97438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 40 kDa.

Target

  • Function

    Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
  • Sequence similarities

    Belongs to the Homer family.
    Contains 1 WH1 domain.
  • Domain

    The WH1 domain interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3.
  • Cellular localization

    Cytoplasm. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density of neuronal cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • HOME3_HUMAN antibody
    • HOMER 3 antibody
    • Homer 3D protein antibody
    • Homer homolog 3 (Drosophila) antibody
    • Homer neuronal immediate early gene 3 antibody
    • Homer protein homolog 3 antibody
    • Homer-3 antibody
    • Homer3 antibody
    • VESL3 antibody
    see all

Images

  • Anti-HOMER3 antibody (ab97438) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

    Predicted band size: 40 kDa



    10% SDS PAGE

References

ab97438 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab97438.
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