Key features and details
- Rabbit polyclonal to Homocysteine
- Suitable for: IHC-P, IP, WB, Dot blot, ELISA
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Homocysteine antibody
See all Homocysteine primary antibodies
DescriptionRabbit polyclonal to Homocysteine
SpecificityCompound Crossreactivity Ratio Homocysteine G BSA 1 Cysteine G BSA 1/423 Homocysteic acid G BSA 1/100,000
Tested applicationsSuitable for: IHC-P, IP, WB, Dot blot, ELISAmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Mammals
Other Immunogen Type corresponding to Homocysteine conjugated to bovine serum albumin (Glutaraldehyde).
Storage instructionsShipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab15154 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration.|
|ELISA||Use at an assay dependent concentration.|
RelevanceHomocysteine is a chemical compound with the formula HSCH2CH2CH(NH2)CO2H. It is a homologue of the naturally-occurring amino acid cysteine, differing in that its side-chain contains an additional methylene (-CH2-) group before the thiol (-SH) group. Alternatively, Homocysteine can be derived from methionine by removing the latter's terminal C methyl group. Elevations of Homocysteine also occur in the rare hereditary disease homocystinuria and in methylene-tetrahydrofolate-reductase deficiency. The latter is quite common and usually goes unnoticed, although there are reports that thrombosis and cardiovascular disease occurs more often in people with elevated Homocysteine.
- (2S) 2 amino 4 sulfanyl butanoic acid antibody
ab15154 has been referenced in 12 publications.
- Kowluru RA et al. Faulty homocysteine recycling in diabetic retinopathy. Eye Vis (Lond) 7:4 (2020). PubMed: 31938715
- Jakubowski H Homocysteine Modification in Protein Structure/Function and Human Disease. Physiol Rev 99:555-604 (2019). PubMed: 30427275
- Kar S et al. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy. Antioxidants (Basel) 8:N/A (2019). PubMed: 31835893
- Hsi E et al. Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia. Int J Ophthalmol 12:38-45 (2019). PubMed: 30662838
- Pushpakumar S et al. Hydrogen Sulfide Protects Hyperhomocysteinemia-Induced Renal Damage by Modulation of Caveolin and eNOS Interaction. Sci Rep 9:2223 (2019). PubMed: 30778103