• Product name

  • Description

    Rabbit polyclonal to HOPX/HOD
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human HOPX/HOD aa 39-67 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q9BPY8

  • Positive control

    • IHC-P: Human kidney tissue. WB: Ramos, A2058 and HEK-293 cell lysate. Flow Cyt: HEK-293 cells.
  • General notes

     This product was previously labelled as HOPX




Our Abpromise guarantee covers the use of ab230544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 8 kDa.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/50.


  • Function

    Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
  • Tissue specificity

    Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Form

    There are 2 isoforms produced by alternative splicing.
  • Alternative names

    • CAMEO antibody
    • heart odd homeobox 1 protein antibody
    • HOD antibody
    • Homeodomain-only protein antibody
    • HOP antibody
    • HOP homeobox antibody
    • HOP_HUMAN antibody
    • HOPX antibody
    • LAGY antibody
    • Lung cancer-associated Y protein antibody
    • NECC1 antibody
    • Not expressed in choriocarcinoma clone 1 antibody
    • Not expressed in choriocarcinoma protein 1 antibody
    • OB1 antibody
    • odd homeobox 1 protein antibody
    • Odd homeobox protein 1 antibody
    • OTTHUMP00000158970 antibody
    • SMAP31 antibody
    • TOTO antibody
    see all


  • Formalin-fixed, paraffin-embedded human kidney tissue stained for HOPX/HOD with ab230544 at 1/100 dilution in immunohistochemical analysis.

  • All lanes : Anti-HOPX/HOD antibody (ab230544) at 1/1000 dilution

    Lane 1 : Ramos (human Burkitt's lymphoma cell line) cell lysate
    Lane 2 : A2058 cell lysate
    Lane 3 : HEK-293 (human epithelial cell line from embryonic kidney) cell lysate

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 8 kDa

  • Flow Cytometry analysis of HEK-293 (Human epithelial cell line from embryonic kidney) cells, labeling HOPX/HOD with ab230544 at a 1/10 dilution (green) compared to a negative control (blue).

    FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


ab230544 has not yet been referenced specifically in any publications.

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