Overview

  • Product name

    Hordenine, Phenylethylamine alkaloid
  • Description

    Phenylethylamine alkaloid
  • Biological description

    Phenylethylamine alkaloid. Selective MAO-B substrate. Indirect adrenergic agent. Increases the release of stored noradrenaline. Inhibits melanogenesis by suppressing cAMP production. Shows positive ionotropic effects in vivo. Orally active.
  • CAS Number

    539-15-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[2-(Dimethylamino)ethyl]phenol
  • Molecular weight

    165.23
  • Molecular formula

    C10H15NO
  • PubChem identifier

    68313
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 25 mM and in ethanol to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)CCC1=CC=C(C=C1)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Kim SC  et al. Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes. Food Chem 141:174-81 (2013). Read more (PubMed: 23768344) »
  • Hapke HJ & Strathmann W [Pharmacological effects of hordenine]. Dtsch Tierarztl Wochenschr 102:228-32 (1995). Read more (PubMed: 8582256) »
  • Barwell CJ  et al. Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. J Pharm Pharmacol 41:421-3 (1989). Read more (PubMed: 2570842) »

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