Overview

  • Product name

  • Description

    Rabbit polyclonal to HOXA1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to Human HOXA1 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: P49639

  • Positive control

    • IHC-P: Human colon tissue. WB: HEK-293T and HeLa whole cell lysate (ab150035). ICC/IF: HeLa cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.01% Sodium azide
    Constituents: PBS, 30% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab230513 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

Target

  • Function

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments.
  • Involvement in disease

    Athabaskan brainstem dysgenesis syndrome
    Bosley-Salih-Alorainy syndrome
  • Sequence similarities

    Belongs to the Antp homeobox family. Labial subfamily.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • BSAS antibody
    • Homeo box A1 antibody
    • Homeobox 1F antibody
    • Homeobox A1 antibody
    • Homeobox protein Hox A1 antibody
    • Homeobox protein Hox-1F antibody
    • Homeobox protein Hox-A1 antibody
    • Hox 1.6 like protein antibody
    • Hox 1F antibody
    • HOX A1 antibody
    • HOX A1 homeodomain protein antibody
    • HOX1 antibody
    • HOX1F antibody
    • hoxa1 antibody
    • hoxb1b antibody
    • HXA1_HUMAN antibody
    • Lab like protein antibody
    • MGC45232 antibody
    see all

Images

  • All lanes : Anti-HOXA1 antibody (ab230513) at 1/500 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
    Lane 2 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate

    Predicted band size: 36 kDa

  • Formalin-fixed, paraffin-embedded human colon tissue stained for HOXA1 using ab230513 at 1/100 dilution in immunohistochemical analysis.

  • Formalin-fixed, 0.1% Triton X-100 permeabilized HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for HOXA1 (red) using ab230513 at 1/100 dilution in ICC/IF, followed by DyLight® 594-conjugated secondary antibody.

References

This product has been referenced in:

  • Liu J  et al. HOXA1 upregulation is associated with poor prognosis and tumor progression in breast cancer. Exp Ther Med 17:1896-1902 (2019). Read more (PubMed: 30783466) »
  • Mao Y  et al. circEIF4G2 modulates the malignant features of cervical cancer via the miR-218/HOXA1 pathway. Mol Med Rep 19:3714-3722 (2019). Read more (PubMed: 30896864) »
See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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