Overview

  • Product name
    Anti-HOXA13 antibody [EPR10357]
    See all HOXA13 primary antibodies
  • Description
    Rabbit monoclonal [EPR10357] to HOXA13
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human HOXA13 aa 250-350. The exact sequence is proprietary.
    Database link: P31271

  • Positive control
    • 293T, K562 and Y79 cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab172570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    • Involvement in disease
      Defects in HOXA13 are the cause of hand-foot-genital syndrome (HFGS) [MIM:140000]; also known as hand-foot-uterus syndrome. The clinical features include small feet with unusually short great toes and abnormal thumbs. Females with the disorder have duplication of the genital tract.
      Defects in HOXA13 are the cause of Guttmacher syndrome (GUTTS) [MIM:176305]. Guttmacher syndrome is a dominantly inherited combination of distal limb and genital tract abnormalities. It has several features in common with hand-foot-genital syndrome, including hypoplastic first digits and hypospadias. Typical features not seen in hand-foot-genital syndrome include postaxial polydactyly of the hands and uniphalangeal second toes with absent nails.
    • Sequence similarities
      Belongs to the Abd-B homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Form
      This protein has also been described in cytoplasm.
    • Alternative names
      • Homeo box 1J antibody
      • Homeo box A13 antibody
      • Homeobox 1J antibody
      • Homeobox A13 antibody
      • Homeobox protein Hox A13 antibody
      • Homeobox protein Hox-1J antibody
      • Homeobox protein Hox-A13 antibody
      • Homeobox protein HOXA13 antibody
      • Homeobox1J antibody
      • HomeoboxA13 antibody
      • HOX 1 antibody
      • HOX 1J antibody
      • Hox 1J protein antibody
      • HOX A13 antibody
      • HOX1 antibody
      • HOX1J antibody
      • HOXA 13 antibody
      • HOXA13 antibody
      • HXA13_HUMAN antibody
      • Transcription factor HOXA13 antibody
      see all

    Images

    • All lanes : Anti-HOXA13 antibody [EPR10357] (ab172570) at 1/1000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : K562 cell lysate
      Lane 3 : Y79 cell lysate

      Lysates/proteins at 10 µg per lane.

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 39 kDa

    References

    ab172570 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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