Key features and details
- Mouse monoclonal [HOX5I043] to HOXA9
- Suitable for: ELISA, WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
Product nameAnti-HOXA9 antibody [HOX5I043]
See all HOXA9 primary antibodies
DescriptionMouse monoclonal [HOX5I043] to HOXA9
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Recombinant fragment
Predicted to work with: Human
Recombinant Human HOXA9
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS
Concentration information loading...
PurityProtein G purified
Purification notesab51236 was purified from culture supernatant of the hybridoma, cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Our Abpromise guarantee covers the use of ab51236 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
|WB||Use at an assay dependent dilution. Predicted molecular weight: 30 kDa.|
FunctionSequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Involvement in diseaseNote=A chromosomal aberration involving HOXA9 is found in a form of acute myeloid leukemia. Translocation t(7;11)(p15;p15) with NUP98.
Note=A chromosomal aberration involving HOXA9 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with MSI2.
Sequence similaritiesBelongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.
- Information by UniProt
FormHOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells.
- ABD-B antibody
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Anti-HOXA9 antibody [HOX5I043] (ab51236)
Predicted band size: 30 kDa
Observed band size: 32 kDa why is the actual band size different from the predicted?
Western blot analysis of immunised recombinant protein..
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ab51236 has not yet been referenced specifically in any publications.