Anti-HoxC6 antibody (ab41587)
Key features and details
- Rabbit polyclonal to HoxC6
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-HoxC6 antibody
See all HoxC6 primary antibodies -
Description
Rabbit polyclonal to HoxC6This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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Host species
Rabbit -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human HoxC6 aa 100-200 conjugated to keyhole limpet haemocyanin.
(Peptide available asab41586) -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
Application | Abreviews | Notes |
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IHC-P | (1) |
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa.
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Notes |
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IHC-P
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa. |
Target
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Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
Sequence similarities
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 3223 Human
- Entrez Gene: 15425 Mouse
- Entrez Gene: 252885 Rat
- Omim: 142972 Human
- SwissProt: P09630 Human
- SwissProt: P10629 Mouse
- Unigene: 549040 Human
- Unigene: 4444 Mouse
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Alternative names
- CP25 antibody
- HHO.C8 antibody
- Homeo box 3C antibody
see all
Images
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All lanes : Anti-HoxC6 antibody (ab41587)
Lane 1 : Human ovary tissue lysate
Lane 2 : Human ovary tumor tissue lysate
Lane 3 : SK-N-BE cell lysate
Lane 4 : PC3 cell lysate
Lane 5 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Exposure time: 8 minutes
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (11)
ab41587 has been referenced in 11 publications.
- Wang Q et al. Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development. Burns Trauma 10:tkac013 (2022). PubMed: 35547861
- Qi ZP et al. HDAC2 promotes the EMT of colorectal cancer cells and via the modular scaffold function of ENSG00000274093.1. J Cell Mol Med 25:1190-1197 (2021). PubMed: 33325150
- Qi L et al. HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/ß-catenin axis in right-sided colon cancer. Cell Death Dis 12:337 (2021). PubMed: 33795652
- Yang P et al. Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma. Cancer Manag Res 11:8167-8179 (2019). PubMed: 31564976
- Zhang F et al. HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-ß/smad signaling pathway in cervical carcinoma cells. Cancer Cell Int 18:204 (2018). PubMed: 30559605