Anti-HPR antibody (ab233006)
Key features and details
- Rabbit polyclonal to HPR
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-HPR antibody
See all HPR primary antibodies -
Description
Rabbit polyclonal to HPR -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Orangutan -
Immunogen
Recombinant fragment (His-T7-tag) corresponding to Human HPR aa 50-350. (Expressed in E.coli).
Database link: P00739 -
Positive control
- WB: Human serum; Recombinant human HPR protein. IHC-P: Human liver, prostate cancer, breast cancer, stomach cancer and colorectal cancer tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab233006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 39 kDa.
|
|
IHC-P |
Use a concentration of 5 - 20 µg/ml.
|
Notes |
---|
WB
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 39 kDa. |
IHC-P
Use a concentration of 5 - 20 µg/ml. |
Target
-
Tissue specificity
In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 Sushi (CCP/SCR) domain. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 454233 Chimpanzee
- Entrez Gene: 100442472 Human
- Entrez Gene: 3250 Human
- Entrez Gene: 100173782 Orangutan
- Omim: 140210 Human
- SwissProt: Q28801 Chimpanzee
- SwissProt: P00739 Human
- SwissProt: Q5R5F6 Orangutan
see all -
Alternative names
- A-259H10.2 antibody
- Haptoglobin related locus antibody
- haptoglobin related protein antibody
see all
Images
-
Formalin-fixed, paraffin-embedded human colorectal cancer tissue stained for HPR using ab233006 at 10 µg/ml in immunohistochemical analysis. DAB staining.
-
Formalin-fixed, paraffin-embedded human stomach cancer tissue stained for HPR using ab233006 at 10 µg/ml in immunohistochemical analysis. DAB staining.
-
Formalin-fixed, paraffin-embedded human breast cancer tissue stained for HPR using ab233006 at 10 µg/ml in immunohistochemical analysis. DAB staining.
-
Formalin-fixed, paraffin-embedded human prostate cancer tissue stained for HPR using ab233006 at 10 µg/ml in immunohistochemical analysis. DAB staining.
-
Formalin-fixed, paraffin-embedded human liver tissue stained for HPR using ab233006 at 10 µg/ml in immunohistochemical analysis. DAB staining.
-
Anti-HPR antibody (ab233006) at 3 µg/ml + Human serum
Secondary
HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution
Predicted band size: 39 kDa -
Anti-HPR antibody (ab233006) at 3 µg/ml + Recombinant human HPR protein
Secondary
HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution
Predicted band size: 39 kDa
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab233006 has been referenced in 2 publications.
- Yan J et al. miR-107 Inhibits the Proliferation of Gastric Cancer Cells In vivo and In vitro by Targeting TRIAP1. Front Genet 13:855355 (2022). PubMed: 35480301
- Jiahui C et al. miR-19b-3p/PKNOX1 Regulates Viral Myocarditis by Regulating Macrophage Polarization. Front Genet 13:902453 (2022). PubMed: 35812737