Overview

  • Product name

  • Description

    Rabbit polyclonal to HPS1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human HPS1 aa 1-324.
    Database link: Q92902

  • Positive control

    • IHC-P: Human small intestine and thymus tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Component of multiple cytoplasmic organelles. Apparently crucial for their normal development and function. May be involved in intracellular protein sorting.
  • Tissue specificity

    Ubiquitous.
  • Involvement in disease

    Defects in HPS1 are the cause of Hermansky-Pudlak syndrome type 1 (HPS1) [MIM:203300]. Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
  • Information by UniProt
  • Database links

  • Alternative names

    • Hermansky Pudlak syndrome 1 protein antibody
    • Hermansky Pudlak syndrome gene antibody
    • Hermansky Pudlak syndrome type 1 antibody
    • Hermansky-Pudlak syndrome 1 antibody
    • Hermansky-Pudlak syndrome 1 protein antibody
    • HPS antibody
    • HPS1 antibody
    • HPS1_HUMAN antibody
    • MGC5277 antibody
    see all

Images

  • Paraffin-embedded human small intestine tissue stained for HPS1 using ab229740 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human thymus tissue stained for HPS1 using ab229740 at 1/100 dilution in immunohistochemical analysis.

References

ab229740 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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