• Product name

    Anti-HPS1 antibody [EP8429(2)]
    See all HPS1 primary antibodies
  • Description

    Rabbit monoclonal [EP8429(2)] to HPS1
  • Host species

  • Tested applications

    Suitable for: WB, ICC/IF, Flow Cyt, IHC-Pmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human HPS1 aa 400-500 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q92902

  • Positive control

    • A375, HeLa, HT-29 and K562 cell lysates; Human breast and muscle tissues; HeLa cells; K562 cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

  • Clone number

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab174301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
ICC/IF 1/50 - 1/100.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


IHC-P 1/50 - 1/100.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Component of multiple cytoplasmic organelles. Apparently crucial for their normal development and function. May be involved in intracellular protein sorting.
    • Tissue specificity

    • Involvement in disease

      Defects in HPS1 are the cause of Hermansky-Pudlak syndrome type 1 (HPS1) [MIM:203300]. Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
    • Information by UniProt
    • Database links

    • Alternative names

      • Hermansky Pudlak syndrome 1 protein antibody
      • Hermansky Pudlak syndrome gene antibody
      • Hermansky Pudlak syndrome type 1 antibody
      • Hermansky-Pudlak syndrome 1 antibody
      • Hermansky-Pudlak syndrome 1 protein antibody
      • HPS antibody
      • HPS1 antibody
      • HPS1_HUMAN antibody
      • MGC5277 antibody
      see all


    • All lanes : Anti-HPS1 antibody [EP8429(2)] (ab174301) at 1/1000 dilution

      Lane 1 : A375 cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : HT-29 cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 79 kDa

    • Immunofluorescent analysis of HeLa cells labeling HPS1 with ab174301 at 1/50 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human breast tissue labeling HPS1 with ab174301 at 1/50 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human muscle tissue labeling HPS1 with ab174301 at 1/50 dilution.

    • Flow cytometric analysis of permeabilized K562 cells with ab174301 at 1/10 dilution (red) compared to a rabbit IgG negative control (green).


    ab174301 has not yet been referenced specifically in any publications.

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