Key features and details
- Rabbit polyclonal to HPS4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-HPS4 antibody
See all HPS4 primary antibodies
DescriptionRabbit polyclonal to HPS4
Tested applicationsSuitable for: WBmore details
Unsuitable for: IP
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide within Human HPS4 aa 658-708. The exact sequence is proprietary.
Database link: Q9NQG7
- WB: HeLa, HEK-293T and Jurkat whole cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate
pH 7 to 8
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAntibody was affinity purified using an epitope specific to HPS4 immobilized on solid support.
Our Abpromise guarantee covers the use of ab241605 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000.|
RelevanceHermansky-Pudlak syndrome is a disorder of organelle biogenesis in which oculocutaneous albinism, bleeding, and pulmonary fibrosis result from defects of melanosomes, platelet dense granules, and lysosomes. Mutations in HPS4 gene as well as several others can cause this syndrome. HPS4 appears to be important in organelle biogenesis and is similar to the mouse 'light ear' protein. Five transcript variants encoding different isoforms have been found for this gene. In addition, transcript variants utilizing alternative polyadenylation signals exist.
Cellular localizationlysosome, melanosome, membrane fraction and platelet dense granule
- Hermansky Pudlak syndrome 4 protein antibody
- Light ear protein homolog antibody
All lanes : Anti-HPS4 antibody (ab241605) at 0.4 µg/ml
Lane 1 : HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Lane 2 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lane 3 : Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell lysate
Lysates/proteins at 50 µg per lane.
Exposure time: 3 minutes
Prepared using NETN lysis buffer.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab241605 has not yet been referenced specifically in any publications.