Key features and details
- Mouse monoclonal [TVG 403] to HPV16 E1+E4
- Suitable for: IHC-Fr, ELISA, Flow Cyt
- Isotype: IgG1
Product nameAnti-HPV16 E1+E4 antibody [TVG 403]
See all HPV16 E1+E4 primary antibodies
DescriptionMouse monoclonal [TVG 403] to HPV16 E1+E4
Tested applicationsSuitable for: IHC-Fr, ELISA, Flow Cytmore details
Species reactivityReacts with: Other species
Fusion protein (Human). Antigen for hybridoma production was expressed as a b-galactosidase fusion protein using the pEX expression system and was consequently cleaved to release the E1/E4 polypeptide.
EpitopeE1/E4 protein is aa 36-41 of human papilloma virus type 16.
This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A/G purified
Primary antibody notesThis antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
Clone numberTVG 403
Our Abpromise guarantee covers the use of ab20190 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||Use at an assay dependent concentration.|
|ELISA||Use at an assay dependent concentration.|
|Flow Cyt||Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
RelevanceHPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans.
- ATP dependent helicase E1 antibody
- E1 antibody
- E4 antibody
ab20190 has been referenced in 1 publication.
- Doorbar J et al. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J Virol 74:10081-95 (2000). PubMed: 11024137