Overview

  • Product name
    Anti-HPV16 L1 antibody [CamVir 1]
    See all HPV16 L1 primary antibodies
  • Description
    Mouse monoclonal [CamVir 1] to HPV16 L1
  • Host species
    Mouse
  • Specificity
    The antibody reacts with a 56 kDa protein in cells infected with L1-vaccinia virus, the protein being present in a predominantly nuclear location. The antibody reacts very strongly with biopsy specimins containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. Cross-reacts with HPV37.
  • Tested applications
    Suitable for: ELISA, WB, IP, IHC-Pmore details
  • Species reactivity
    Reacts with: Human papillomavirus
  • Immunogen

    Human papilloma virus type 16, major capsid protein L1.

Properties

Applications

Our Abpromise guarantee covers the use of ab69 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration. PubMed: 20600940
WB Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • Relevance
    L1 is a major capsid protein of type 16 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
  • Cellular localization
    Virion. Host Nucleus.
  • Database links
    • Alternative names
      • HPV-16 antibody
      • HPV-16 capsid antibody
      • HPV16 capsid protein antibody
      • HPV16 L1 antibody
      • HPV16 major capsid protein L1 antibody
      • Human papillomavirus type 16 L1 antibody
      • Human papillomavirus type 16 major capsid protein L1 antibody
      • L1 antibody
      • Major capsid L1 protein antibody
      • Major capsid protein antibody
      • Major capsid protein L1 antibody
      see all

    References

    This product has been referenced in:
    • Day PM  et al. Interferon Gamma Prevents Infectious Entry of Human Papillomavirus 16 via an L2-Dependent Mechanism. J Virol 91:N/A (2017). WB . Read more (PubMed: 28250129) »
    • Lamprecht RL  et al. Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells. Sci Rep 6:20431 (2016). Read more (PubMed: 26853456) »

    See all 13 Publications for this product

    Publishing research using ab69? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Submit a review Submit a question

    13 reviews or Q&A

    10
    Votes: Highest First

    Thank you very much for the information.
    I am however looking for the binding site of your camVir1 antibody. That is against HPV16 L1. Do you have a paper on that?
    Thanking you for your help

    Thank you for contacting us.

    Unfortunately, we do not have any other information about the binding site, I am afraid!. The CamVir1 clone is a published clone, please check the literature if anybody else have published any more details about th...

    Read More

    Product code: 69
    Inquiry: Hi, Which epitope on L1 does camvir1 bind to? Thanks Inga

    Thank you for contacting us.

    The exact epitope sequence has been mapped. The immunogen is a gel-purified HPV-18 E6-b galactosidase fusion protein.

    Please check the link below of original publication;

    http://vir.sgmjournals.or...

    Read More

    What is the epitope of antibody ab69?

    Thank you for contacting us.

    Please find attached the requested paper.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Use our products? Submit an Ab...

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    Dear technical team,

    Our customer is going to purchase ab69 and she would like to know if it has cross-reactivity to other HPV types except type 16.
    Please let me know.

    Best regards

    Thank you for contacting us.

    The anti-HPV16 L1 antibody [CamVir 1] (ab69) has shown some cross reactivity with other HPV types other than 16.The antibody reacts very strongly with biopsy specimens containing HPV-16 or -33, whilstvery weak rea...

    Read More

    Hola de nuevo Abcam:
    Uno de nuestros clientes adquirió estos 3 anticuerpos con nosotros, ellos los alicuotaron y almacenaron a -20°C, ahora que tratan de usarlos ninguno de los tres funciona, nos podrán ayudar, aún est&aac...

    Read More

    Gracias por contactarnos de nuevo.

    ¿Podrías por favor indicarme el número de pedido en el que se enviaron los anticuerpos? ¿En qué estado se recibieron? ¿Nada más recibirlos se alicuotaron y gu...

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    Thank you what is the status of our order?

    Unfortunately shipment of this order is being held up by our accounts team.

    Our accounting department can be contacted by email at mailto:us.credits@abcam.com or by telephone using the information at the Contact Us link in the top right corne...

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    I purchased your mouse anti-HPV 16 L1 ab a while back. I am using the ab for ELISA purposes (to test levels of HPV specific IgG). I am trying to figure out appropriate standards for my ELISA. At first, I was thinking that I might coat a plate with anti...

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    Thank you for contacting us.


    If I understand you correctly. The anti-mouse IgG would recognize your purified normal mouse IgG or it would recognize Ab69. These, in turn, would be recognized by goat anti-mouse HRP. However if you are to ...

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    To Whom It May Concern:   I am requesting an MSDS (Material Safety Data Sheet) for a product used by a client of mine, Thunder Bay Regional Research.  The products are as follows:   -HPV16 L1 (product code: ab69) -HPV16 E2 (product code: ab17185) -mous...

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    Thank you for contacting Abcam. I have attached the MSDS for all except ab500, ChIP kit. I am still waiting for the laboratory to get back to me on that one and I will send it on as soon as I get it. If there is anything else I can do, please let me ...

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    Dear technical team,   Our customer would like to know more information about immunogen of ab69 and ab30908.   If you have information of amino acid sequence, please let me know.   Thank you in advance.

    Thank you for your inquiry. Both Anti-HPV16 L1 recognise HPV Type 16, L1 (major capsid protein). Unfortunately, we do not currently have more information about the epitopes for those monoclonal antibodies. We will update the on-line data...

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    We routinely buy antibodies from Abcam, so I was wondering if you could send us a small amount of the ab69 HPV16-L1 (CamVir 1) antibody to test before we purchase a larger amount.

    Thank you for your email. We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not work as specified on the datasheet, we will offer a replacement or reimbursement. Should you d...

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    1-10 of 13 Abreviews or Q&A

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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