Key features and details
- Mouse monoclonal [CamVir 1] to HPV16 L1
- Suitable for: ELISA, WB, IP, IHC-P
- Reacts with: Human papillomavirus
- Isotype: IgG2a
Product nameAnti-HPV16 L1 antibody [CamVir 1]
See all HPV16 L1 primary antibodies
DescriptionMouse monoclonal [CamVir 1] to HPV16 L1
SpecificityThe antibody reacts with a 56 kDa protein in cells infected with L1-vaccinia virus, the protein being present in a predominantly nuclear location. The antibody reacts very strongly with biopsy specimins containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. Cross-reacts with HPV37.
Tested applicationsSuitable for: ELISA, WB, IP, IHC-Pmore details
Species reactivityReacts with: Human papillomavirus
Human papilloma virus type 16, major capsid protein L1.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPhosphate buffered saline
Concentration information loading...
PurityProtein A purified
Clone numberCamVir 1
Light chain typeunknown
Our Abpromise guarantee covers the use of ab69 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration. PubMed: 20600940|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.|
|IP||Use at an assay dependent concentration.|
|IHC-P||Use at an assay dependent concentration.|
RelevanceL1 is a major capsid protein of type 16 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
Cellular localizationVirion. Host Nucleus.
- HPV-16 antibody
- HPV-16 capsid antibody
- HPV16 capsid protein antibody
ab69 has been referenced in 15 publications.
- Xv Z et al. Effective Neutralizing Antibody Produced in Mice Directly Immunized with Integrated Pichia pastoris Expressing HPV16L1 Protein. Viral Immunol 32:308-317 (2019). PubMed: 31381497
- Day PM et al. Interferon Gamma Prevents Infectious Entry of Human Papillomavirus 16 via an L2-Dependent Mechanism. J Virol 91:N/A (2017). WB . PubMed: 28250129
- Grant BD et al. A paper-based immunoassay to determine HPV vaccination status at the point-of-care. Vaccine 34:5656-5663 (2016). PubMed: 27667331
- Lamprecht RL et al. Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells. Sci Rep 6:20431 (2016). PubMed: 26853456
- Warren CJ et al. The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS One 9:e96579 (2014). WB . PubMed: 24827144