Anti-HPV16 L1 antibody [CamVir 1] (ab69)
Key features and details
- Mouse monoclonal [CamVir 1] to HPV16 L1
- Suitable for: WB, IP, IHC-P
- Reacts with: Human papillomavirus
- Isotype: IgG2a
Overview
-
Product name
Anti-HPV16 L1 antibody [CamVir 1]
See all HPV16 L1 primary antibodies -
Description
Mouse monoclonal [CamVir 1] to HPV16 L1 -
Host species
Mouse -
Specificity
The antibody reacts with a 56 kDa protein in cells infected with L1-vaccinia virus, the protein being present in a predominantly nuclear location. The antibody reacts very strongly with biopsy specimins containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. Cross-reacts with HPV37. -
Tested applications
Suitable for: WB, IP, IHC-Pmore details -
Species reactivity
Reacts with: Human papillomavirus -
Immunogen
Fusion protein corresponding to Human papillomavirus HPV16 L1. A b galactosidase-L1 fusion protein purified by PAGE.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Phosphate buffered saline -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
CamVir 1 -
Myeloma
NS0 -
Isotype
IgG2a -
Light chain type
unknown -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab69 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.
|
|
IP |
Use at an assay dependent concentration.
|
|
IHC-P |
Use at an assay dependent concentration.
|
Notes |
---|
WB
Use at an assay dependent concentration. Predicted molecular weight: 56 kDa. |
IP
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
Target
-
Relevance
L1 is a major capsid protein of type 16 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. -
Cellular localization
Virion. Host Nucleus. -
Database links
- Entrez Gene: 1489082 Human papillomavirus
- SwissProt: P03101 Human papillomavirus
-
Alternative names
- HPV-16 antibody
- HPV-16 capsid antibody
- HPV16 capsid protein antibody
see all
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (20)
ab69 has been referenced in 20 publications.
- Karimi H et al. Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer. Sci Rep 10:5787 (2020). PubMed: 32238821
- Mboumba Bouassa RS et al. Serum and cervicovaginal IgG immune responses against a7 and a9 HPV in non-vaccinated women at risk for cervical cancer: Implication for catch-up prophylactic HPV vaccination. PLoS One 15:e0233084 (2020). PubMed: 32421735
- Ðuraševic S et al. The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats. Int J Mol Sci 20:N/A (2019). PubMed: 31731785
- Wu X et al. Induction of neutralizing antibodies by human papillomavirus vaccine generated in mammalian cells. Antib Ther 2:45-53 (2019). PubMed: 33928221
- Xv Z et al. Effective Neutralizing Antibody Produced in Mice Directly Immunized with Integrated Pichia pastoris Expressing HPV16L1 Protein. Viral Immunol 32:308-317 (2019). PubMed: 31381497