Overview

  • Product name
    Anti-HPV18 L1 antibody [M8011538]
    See all HPV18 L1 primary antibodies
  • Description
    Mouse monoclonal [M8011538] to HPV18 L1
  • Host species
    Mouse
  • Specificity
    This antibody recognizes the major capsid protein L1. The clone number has been updated from (8.F.324) to (M8011538) both clone numbers name the same antibody clone. Crossreactivity: HPV 16.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human papillomavirus
  • Immunogen

    Tissue, cells or virus corresponding to HPV18 L1. Human Papilloma Virus type 18.

Properties

Applications

Our Abpromise guarantee covers the use of ab31492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 58 kDa.

Target

  • Relevance
    L1 is a major capsid protein of type 18 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
  • Cellular localization
    Virion
  • Database links
    • Alternative names
      • L1 antibody
      • HPV18 major capsid protein L1 antibody
      • Human papilloma virus type 18 major capsid protein L1 antibody
      • Human papillomavirus type 18 L1 antibody
      • Human papillomavirus type 18 major capsid protein L1 antibody
      • Major capsid protein L1 antibody
      see all

    References

    ab31492 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    1-10 of 16 Abreviews or Q&A

    Question
    Answer

    Thank you very much for your call today.

    I have attached the certificate of compliance for the lot of ab31492 you've requested. Please let me know if you have any questions or if there is anything else that we can do for you, and I'll be happy to help.

    Have a nice day.

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    Answer

    Thank you for contacting us.

    Your credit note ID is XXXXX.

    I am sorry that this antibody did not perform as stated on the datasheet, I have asked our Finance department to issue a credit note for you. The credit note may be used in one of the following ways:

    (1) Redeemed against the original invoice if this hasn't already been paid.
    (2) Held on the account for use against a future order.
    (3) A full refund can be offered where no other invoices are outstanding.

    Please contact your Finance department to confirm how you would like the credit note to be used and ensure it is not redeemed without your knowledge.

    To specifically receive a refund please ask your Finance department to contact our Finance department at creditcontrol@abcam.com or by telephone using the information at the “Contact Us” link in the top right corner of our website.

    The credit note ID is for your reference only, please refer to the credit note ID in any correspondence with our accounting department. We will send you the completed credit note by email or postal mail with the actual credit note number which will start with the letters CGB.

    I hope this experience will not prevent you from purchasing other products from us in the future. Our Scientific Support team is always at your service should you require further expert advice

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    Answer

    One vial of ab69 has been added in order 1118799 as a replacement of ab30908 from order 107411.

    There was only one vial of ab30908 in order 107411 so the credit note cannot be provided.

    Please let me know if you have any question.

    Many thanks for your cooperation in this case.

    Read More

    Answer

    Thank you for your response.

    Currently, we have the same purification for both antibodies (your customer has used)in stock and we are unable to offer new batches as replacements at the moment.

    Please discuss it with your customer and let me know how you wish to proceed. We look forward to hearing from you soon.

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    Answer

    Thank you for your response.

    My colleague is out of office for the rest of the week. I have checked stock/batch availability for both antibodies and currently we have the same batch (purification for both antibodies ab30908 and ab31492) and are unable to offer new batches.

    Could you please discuss with your customer and let us know how you wish to proceed with this enquiry.

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    Answer

    Thank you for your email and for your patience.

    I am sorry we are unable to determine the reason why these antibodies are binding to HCT116 cell line lysates. We have never tested these antibodies with HCT116 and we haven't so we are unable provide any help in this case.

    Our recommendations is searching and trying a different negative control cell line, for results comparison.

    I hope this information is nevertheless helpful to you. Please do not hesitate to contact me in case you require any further information.

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    Answer

    Thank you for your reply.

    Your credit note ID is *******.

    I am sorry that this antibodies did not perform as stated on the datasheets. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact our accounting department so that we may gather the correct information needed for the refund. To avoid confusion, please ensure your accounts department is aware of how the credit note is being used.

    Our accounting department can be contacted by email at us.credits@abcam.com or by telephone using the information at the Contact Us link in the top right corner of our website. Please refer to the credit note ID in any correspondence with our accounting department.

    The credit note ID is for your reference only and does not automatically guarantee the credit.

    I hope this experience will not prevent you from purchasing other products from us in the future. Our Scientific Support team is always at your service, should you require further expert advice.

    Read More

    Answer

    Thank you for your reply.

    I will gladly provide a replacement product for ab31491 (anti-HPV11) as we state ELISA as a covered application. Please let me know if you would like the same product or another such as one of the three HPV11 antibodies which I have suggested (https://www.abcam.com/HPV11-E7-antibody-9H5-ab100967.html,https://www.abcam.com/HPV11-E2-antibody-10E12-ab100968.html,https://www.abcam.com/HPV11-E7-antibody-711-66-ab53195.html) or another.

    I cannot replace or refundab31492 (anti-HPV18). We do not recommend this in or guarantee it in ELISA but only in western blot.

    If you would like to provide any troubleshooting steps (have you changed blocking solutions, adjusted antibody concentration, etc.) about your ELISA experiment with ab31492, I would be very happy to review these and offer suggestions which may help.

    I look forward to hearing from you. Please do not hesitate to contact us if you need any more advice or information.

    Use our products? Submit an Abreview. Earn rewards!
    https://www.abcam.com/abreviews

    Read More

    Answer

    Thank you for your reply and for this additional information.

    I would like to clarify a few things as I am a little confused at how best to serve you here. I would like to make sure we are both on the same page.

    You have purchased our anti-HPV11 (cat# ab31491) and anti- HPV18 (cat# ab31492) for use in ELISA. Anti-HPV11 (cat# ab31491) has ELISA listed as tested application and is covered by our Abpromise guarantee.

    However, anti- HPV18 (cat# ab31492) does not have ELISA listed as tested application but only Western blot. As we have not tested this product in ELISA, we cannot be sure how or if it would perform in ELISA. As such this product is not covered by our Abpromise guarantee. Details about our Abpromise may be found at: https://www.abcam.com/index.html?pageconfig=abpromise

    I will gladly provide a replacement product for ab31491 (anti-HPV11) as we state ELISA as a covered application. While I cannot replace or refundab31492 (anti-HPV18) as we do not guarantee it in ELISA, I would be very happy to provide scientific support to help you to get the best response possible in ELISA.If you would like to provide any additional details and troubleshooting steps about your ELISA experiment with ab31492, I would be very happy to review these and offer suggestions which may help.

    As you have requested, I can replace ab31491 (anti-HPV11) for you. Would you prefer a new vial of this product or another product? We do offer three other anti-HPV11 products tested in ELISA,https://www.abcam.com/HPV11-E7-antibody-9H5-ab100967.html,https://www.abcam.com/HPV11-E2-antibody-10E12-ab100968.html,https://www.abcam.com/HPV11-E7-antibody-711-66-ab53195.html.

    I look forward to your reply. Please let me know if you have any questions or there are other ways that Abcam may help you meet your research goals.

    Read More

    Answer

    Thank you for providing these detail which not only help us to understand the difficulties which you have been experiencing but are very valuable to us should the need arise for us to do further internal testing of these products.

    OurAnti-HPV11 L1 antibody [8.F.319], ab31491 is covered by our Abpromise guarantee for use in ELISA. Howeverab31492, Anti-HPV18 L1 antibody [8.F.324], has only been tested and guaranteed in western blot.Under the terms of our Abpromise guarantee we provide scientific support, replacement or refund for a period of six months from purchase should this product not perform as indicated on the datasheet. More information on our Abpromise may be found at the following link:https://www.abcam.com/index.html?pageconfig=abpromise

    While I do recognize your expertise when using product in ELISA, in order to determine whether we can be of assistance with scientific support we ask for protocol and troubleshooting information which may have been performed when using the product. We may be able to offer expert advice when using our products in your assay.

    We do have one other HPV6 antibody,https://www.abcam.com/HPV6-E7-antibody-B973M-ab104726.html,which has been tested in ELISA. I can send this to you free of charge as a replacement for ab31491. If you could please provide the Abcam order confirmation for the original purchase I can process this replacement for you.

    I look forward to your reply. . Please let me know if you have any questions or there are other ways that Abcam may help you meet your research goals.

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    1-10 of 16 Abreviews or Q&A

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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