Overview

  • Product name

    HQNO, antagonist of dihydrostreptomycin
  • Description

    Multifunctional compound. Various pharmacological effects.
  • Biological description

    Multifunctional compound. Various pharmacological effects. Respiratory chain inhibitor that blocks mitochondrial complex I, III and NADH oxidase activity. Mitochondrial metabolism modifier. Antagonist of dihydrostreptomycin. Active in vitro.
  • Purity

    > 99%
  • CAS Number

    341-88-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kim MS & Kim YJ Enzymatic properties of the membrane-bound NADH oxidase system in the aerobic respiratory chain of Bacillus cereus. J Biochem Mol Biol 37:753-6 (2004). Read more (PubMed: 15607037) »
  • Howell N  et al. Mammalian mitochondrial mutants selected for resistance to the cytochrome b inhibitors HQNO or myxothiazol. Somatic Cell Genet 9:721-43 (1983). Read more (PubMed: 6318375) »
  • Van Ark G & Berden JA Binding of HQNO to beef-heart sub-mitochondrial particles. Biochim Biophys Acta 459:119-27 (1977). Read more (PubMed: 831781) »

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