Overview

  • Product name

  • Description

    Rabbit polyclonal to HRH1/H1R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human HRH1/H1R aa 70-323.
    Database link: P35367

  • Positive control

    • 293T, A431, HeLa, HepG2 whole cell lysate (ab7900); Cal27 xenograft.
  • General notes

    Previously labelled as HRH1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab154158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BPHS, mouse, homolog of antibody
    • H1 R antibody
    • H1R antibody
    • HH1R antibody
    • HisH1 antibody
    • Histamine H(1) receptor antibody
    • Histamine H1 receptor antibody
    • Histamine receptor H1 antibody
    • Histamine receptor subclass H1 antibody
    • Hrh1 antibody
    • HRH1_HUMAN antibody
    see all

Images

  • All lanes : Anti-HRH1/H1R antibody (ab154158) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : HeLa whole cell lysate
    Lane 4 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 56 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Cal27 xenograft tissue labeling HRH1/H1R with ab154158 at 1/500 dilution.

References

ab154158 has not yet been referenced specifically in any publications.

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