Overview

  • Product name

  • Description

    Goat polyclonal to HRH1/H1R
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human HRH1/H1R aa 170-183 (internal sequence).
    Sequence:

    QQTSVRREDKCETD


    Database link: NP_000852.1

  • Positive control

    • Human heart lysate.
  • General notes

    Previously labelled as HRH1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab77100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 56 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 2 - 4 µg/ml.

Target

  • Function

    In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BPHS, mouse, homolog of antibody
    • H1 R antibody
    • H1R antibody
    • HH1R antibody
    • HisH1 antibody
    • Histamine H(1) receptor antibody
    • Histamine H1 receptor antibody
    • Histamine receptor H1 antibody
    • Histamine receptor subclass H1 antibody
    • Hrh1 antibody
    • HRH1_HUMAN antibody
    see all

Images

  • Immunohistochemistry (paraffin-embedded sections) analysis of human lung tissue labeling HRH1/H1R with ab77100 at 4µg/ml. Microwaved antigen retrieval was performed using Tris/EDTA buffer pH 6. HRP staining.

  • Anti-HRH1/H1R antibody (ab77100) at 0.5 µg/ml + Heart lysate (in RIPA buffer) at 35 µg

    Predicted band size: 56 kDa
    Observed band size: 56 kDa

References

ab77100 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab77100.
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