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  1. Link

    hrp-c-reactive-protein-antibody-ab19175.pdf

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Immunology Innate Immunity Macrophage / Inflamm.
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HRP Anti-C Reactive Protein antibody (ab19175)

  • Datasheet
  • SDS
Submit a review Submit a question References (3)

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Key features and details

  • HRP Goat polyclonal to C Reactive Protein
  • Suitable for: ELISA, ICC, WB
  • Reacts with: Human
  • Conjugation: HRP
  • Isotype: IgG

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Overview

  • Product name

    HRP Anti-C Reactive Protein antibody
    See all C Reactive Protein primary antibodies
  • Description

    HRP Goat polyclonal to C Reactive Protein
  • Host species

    Goat
  • Conjugation

    HRP
  • Specificity

    By immunoelectrophoresis and ELISA this antibody reacts specifically with human C Reactive Protein.
  • Tested applications

    Suitable for: ELISA, ICC, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein. This information is proprietary to Abcam and/or its suppliers.

  • General notes

    Molar enzyme/antibody protein ratio is 4:1.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 6.8
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.19% HEPES, 0.58% Sodium chloride, 0.2% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Acute Phase Reactants
    • Immunology
    • Innate Immunity
    • Complement
    • Classical Pathway
    • Epigenetics and Nuclear Signaling
    • Chromatin Binding Proteins
    • DNA / RNA binding
    • Cardiovascular
    • Atherosclerosis
    • Vascular Inflammation
    • Inflammatory mediators
    • Cardiovascular
    • Heart
    • Apoptosis
    • Metabolism
    • Types of disease
    • Metabolic disorders
    • Neuroscience
    • Processes

Associated products

  • Recombinant Protein

    • Recombinant Human C Reactive Protein (ab167710)
  • Related Products

    • TMB ELISA Substrate (Highest Sensitivity) (ab171522)
    • TMB ELISA Substrate (High Sensitivity) (ab171523)
    • TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
    • TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
    • TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
    • TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
    • 450 nm Stop Solution for TMB Substrate (ab171529)
    • 650 nm Stop Solution for TMB Substrate (ab171531)
    • Immunoassay Blocking Buffer (ab171534)
    • Immunoassay Blocking (BSA Free) (ab171535)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab19175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Use at an assay dependent concentration.
ICC
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration. Predicted molecular weight: 25 kDa.

(Colorimetric detection), 1/1000 - 30000 (Chemiluminescent detection).

Notes
ELISA
Use at an assay dependent concentration.
ICC
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration. Predicted molecular weight: 25 kDa.

(Colorimetric detection), 1/1000 - 30000 (Chemiluminescent detection).

Target

  • Function

    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • Tissue specificity

    Found in plasma.
  • Sequence similarities

    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P02741 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1401 Human
    • Omim: 123260 Human
    • SwissProt: P02741 Human
    • Unigene: 709456 Human
    • Unigene: 76452 Human
    • Alternative names

      • Pentraxin 1, short antibody
      • C reactive protein antibody
      • C reactive protein pentraxin related antibody
      • C-reactive protein(1-205) antibody
      • CRP antibody
      • CRP_HUMAN antibody
      • MGC88244 antibody
      • Pentraxin 1 antibody
      • PTX 1 antibody
      • PTX1 antibody
      see all

    Protocols

    • Western blot protocols
    • Immunocytochemistry & immunofluorescence protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (3)

    Publishing research using ab19175? Please let us know so that we can cite the reference in this datasheet.

    ab19175 has been referenced in 3 publications.

    • Kim WJ  et al. Synergistic Use of Gold Nanoparticles (AuNPs) and "Capillary Enzyme-Linked Immunosorbent Assay (ELISA)" for High Sensitivity and Fast Assays. Sensors (Basel) 18:N/A (2017). PubMed: 29278402
    • Hamon Y  et al. Proteolytic cleavage of the long pentraxin PTX3 in the airways of cystic fibrosis patients. Innate Immun 19:611-22 (2013). PubMed: 23475792
    • Trilok-Kumar G  et al. Effect of vitamin D supplementation of low birth weight term Indian infants from birth on cytokine production at 6 months. Eur J Clin Nutr 66:746-50 (2012). Sandwich ELISA . PubMed: 22510791

    Customer reviews and Q&As

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