Key features and details
- HRP Mouse monoclonal [C6] to C Reactive Protein
- Suitable for: ELISA, Sandwich ELISA
- Reacts with: Human
- Conjugation: HRP
- Isotype: IgG2a
Related conjugates and formulations
Product nameHRP Anti-C Reactive Protein antibody [C6]
See all C Reactive Protein primary antibodies
DescriptionHRP Mouse monoclonal [C6] to C Reactive Protein
Tested applicationsSuitable for: ELISA, Sandwich ELISAmore details
Species reactivityReacts with: Human
Full length native protein (purified) (Human)
Specific antibody titer in ELISA is > 10-6.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.05% Proclin 300
Constituents: 0.8% Sodium chloride, 0.02% Potassium chloride, 0.18% Dibasic monohydrogen sodium phosphate, 0.024% Monobasic dihydrogen potassium phosphate
Concentration information loading...
PurityProtein A purified
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
- TMB ELISA Substrate (High Sensitivity) (ab171523)
- TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
- TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
- TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
- TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
- 450 nm Stop Solution for TMB Substrate (ab171529)
- 650 nm Stop Solution for TMB Substrate (ab171531)
- Immunoassay Blocking Buffer (ab171534)
- Immunoassay Blocking (BSA Free) (ab171535)
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24462 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
sELISA: Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [C5] to C Reactive Protein (ab8279) and Mouse monoclonal [C7] to C Reactive Protein (ab8280).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionDisplays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Tissue specificityFound in plasma.
Sequence similaritiesBelongs to the pentaxin family.
Contains 1 pentaxin domain.
- Information by UniProt
- Pentraxin 1, short antibody
- C reactive protein antibody
- C reactive protein pentraxin related antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab24462 has been referenced in 4 publications.
- Loukov D et al. Monocyte activation is elevated in women with knee-osteoarthritis and associated with inflammation, BMI and pain. Osteoarthritis Cartilage 26:255-263 (2018). PubMed: 29128509
- Verschoor CP et al. DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly. Exp Gerontol 105:47-52 (2018). Sandwich ELISA . PubMed: 29032243
- Verschoor CP et al. Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents. J Infect Dis 216:191-197 (2017). PubMed: 28838148
- Skogstrand K et al. Effects of blood sample handling procedures on measurable inflammatory markers in plasma, serum and dried blood spot samples. J Immunol Methods 336:78-84 (2008). PubMed: 18495149