HRP Anti-HIV1 gp41 antibody (ab68622)
Key features and details
- HRP Goat polyclonal to HIV1 gp41
- Suitable for: IHC-Fr, WB, ELISA
- Conjugation: HRP
- Isotype: IgG
Overview
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Product name
HRP Anti-HIV1 gp41 antibody
See all HIV1 gp41 primary antibodies -
Description
HRP Goat polyclonal to HIV1 gp41 -
Host species
Goat -
Conjugation
HRP -
Specificity
This antibody reacts with HIV1 gp41 in viral and infected tissue samples. -
Tested applications
Suitable for: IHC-Fr, WB, ELISAmore details -
Species reactivity
Reacts with: Other species -
Immunogen
Recombinant fragment, corresponding to the ectodomain of gp41-glycosylated (a.a. residues 546-682) from strain HxB2.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: 1% BSA, PBS -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Recombinant Protein
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Applications
Our Abpromise guarantee covers the use of ab68622 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr | 1/20. | |
WB | 1/20. Predicted molecular weight: 41 kDa. | |
ELISA | 1/200. |
Target
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Relevance
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes. -
Alternative names
- Env antibody
- Glycoprotein 41 antibody
- gp41 antibody
see all
Protocols
References (1)
ab68622 has been referenced in 1 publication.
- Zhou X et al. Alpha-1-antitrypsin interacts with gp41 to block HIV-1 entry into CD4+ T lymphocytes. BMC Microbiol 16:172 (2016). WB ; Human . PubMed: 27473095