HRP Anti-Influenza A Virus Nucleoprotein antibody [C43] (ab176837)
Key features and details
- HRP Mouse monoclonal [C43] to Influenza A Virus Nucleoprotein
- Suitable for: IHC, ELISA, WB, ICC
- Reacts with: Influenza A
- Conjugation: HRP
- Isotype: IgG2a
Overview
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Product name
HRP Anti-Influenza A Virus Nucleoprotein antibody [C43]
See all Influenza A Virus Nucleoprotein primary antibodies -
Description
HRP Mouse monoclonal [C43] to Influenza A Virus Nucleoprotein -
Host species
Mouse -
Conjugation
HRP -
Tested applications
Suitable for: IHC, ELISA, WB, ICCmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
Tissue, cells or virus corresponding to Influenza A Virus Nucleoprotein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 6
Constituents: Glycerol, PBS -
Concentration information loading... -
Purity
Proprietary Purification -
Purification notes
Purity >90% by SDS-PAGE. -
Clonality
Monoclonal -
Clone number
C43 -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Recombinant Protein
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Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab176837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC |
1/200.
|
|
| ELISA |
Use at an assay dependent concentration.
|
|
| WB |
1/300 - 1/1000. Predicted molecular weight: 56 kDa.
|
|
| ICC |
1/200.
|
| Notes |
|---|
|
IHC
1/200. |
|
ELISA
Use at an assay dependent concentration. |
|
WB
1/300 - 1/1000. Predicted molecular weight: 56 kDa. |
|
ICC
1/200. |
Target
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Relevance
The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002). -
Cellular localization
Host cell nucleus -
Database links
- Entrez Gene: 956531 Influenza A
- SwissProt: P03466 Influenza A
- SwissProt: P69291 Influenza A
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Alternative names
- Common flu NP antibody
- Influenza A virus NP antibody
- NP antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab176837 has not yet been referenced specifically in any publications.
