HRP Anti-Matrix protein 1 antibody (ab21008)

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Key features and details

  • HRP Goat polyclonal to Matrix protein 1
  • Suitable for: ELISA, ICC/IF, WB
  • Reacts with: Species independent
  • Conjugation: HRP
  • Isotype: IgG

Overview

  • Product name

    HRP Anti-Matrix protein 1 antibody
    See all Matrix protein 1 primary antibodies

  • Description

    HRP Goat polyclonal to Matrix protein 1

  • Host species

    Goat

  • Conjugation

    HRP

  • Tested applications

    Suitable for: ELISA, ICC/IF, WBmore details
    Unsuitable for: IHC

  • Species reactivity

    Reacts with: Species independent

  • Immunogen

    Full length native protein (purified) corresponding to Matrix protein 1. Purified M1 protein, Influenza A-Phillipines (H3N2).

  • General notes

    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

    The antibody is covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab21008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Use at an assay dependent dilution.
ICC/IF
Use at an assay dependent dilution.
WB
Use a concentration of 1 µg/ml.
Notes
ELISA
Use at an assay dependent dilution.
ICC/IF
Use at an assay dependent dilution.
WB
Use a concentration of 1 µg/ml.
  • Application notes
    Is unsuitable for IHC.

    • Target

    • Relevance

      Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions.

    • Cellular localization

      Cytoplasmic

    • Alternative names

      • M1 antibody
      • Matrix Protein 1 antibody
      • Matrix Protein I antibody
      • Membrane matrix protein M1 antibody

    References (1)

    Publishing research using ab21008? Please let us know so that we can cite the reference in this datasheet.

    ab21008 has been referenced in 1 publication.

    • Poon LL  et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol 182:3063-71 (2009). WB . PubMed: 19234203

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