HRP Anti-Matrix protein 1 antibody (ab21008)

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Key features and details

  • HRP Goat polyclonal to Matrix protein 1
  • Suitable for: ELISA, ICC/IF, WB
  • Reacts with: Species independent
  • Conjugation: HRP
  • Isotype: IgG

Overview

  • Product name

    HRP Anti-Matrix protein 1 antibody
    See all Matrix protein 1 primary antibodies

  • Description

    HRP Goat polyclonal to Matrix protein 1

  • Host species

    Goat

  • Conjugation

    HRP

  • Tested applications

    Suitable for: ELISA, ICC/IF, WBmore details
    Unsuitable for: IHC

  • Species reactivity

    Reacts with: Species independent

  • Immunogen

    Full length native protein (purified) corresponding to Matrix protein 1. Purified M1 protein, Influenza A-Phillipines (H3N2).

  • General notes

    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

    The antibody is covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

Our Abpromise guarantee covers the use of ab21008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
WB Use a concentration of 1 µg/ml.
  • Application notes
    Is unsuitable for IHC.

    • Target

    • Relevance

      Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions.

    • Cellular localization

      Cytoplasmic

    • Alternative names

      • M1 antibody
      • Matrix Protein 1 antibody
      • Matrix Protein I antibody
      • Membrane matrix protein M1 antibody

    References (1)

    Publishing research using ab21008? Please let us know so that we can cite the reference in this datasheet.

    ab21008 has been referenced in 1 publication.

    • Poon LL  et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol 182:3063-71 (2009). WB . PubMed: 19234203

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