HRP Anti-Mycobacterium tuberculosis antibody (ab21189)

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Key features and details

  • HRP Rabbit polyclonal to Mycobacterium tuberculosis
  • Suitable for: IHC-P
  • Reacts with: Species independent
  • Conjugation: HRP
  • Isotype: IgG

Overview

  • Product name

    HRP Anti-Mycobacterium tuberculosis antibody
    See all Mycobacterium tuberculosis primary antibodies

  • Description

    HRP Rabbit polyclonal to Mycobacterium tuberculosis

  • Host species

    Rabbit

  • Conjugation

    HRP

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Species independent

  • Immunogen

    Tissue/ cell preparation.Purified PPD

  • General notes

    IgG fraction covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while reserving maximum enzyme activity. Free enzyme is absent. Estimated Molar HRP: IgG substitution is 2-3

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C.

  • Storage buffer

    Preservative: 0.002% Thimerosal (merthiolate)
    Constituents: PBS, 1% BSA
  • Concentration information loading...

  • Purity

    IgG fraction

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab21189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent dilution.

Target

  • Relevance

    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.

  • Alternative names

    • M. tuberculosis antibody

References (0)

Publishing research using ab21189? Please let us know so that we can cite the reference in this datasheet.

ab21189 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Question

I am looking for antimycobacterium antibodies for immunohistochemistry and got interested with your products ab20027 and also ab21189 and ab905. Concerning first two products I have a question what dilution is recommended for them? What does "use at an assay dependent dilution" means? Secondly, in the ab21189 datasheet nothing is said about antigen retrieval. Does it mean that no retrieval is required the same as for ab20027?

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Answer

As a follow up to my previous message, I can now confirm that ab21189 does not require antigen retrieval. I hope this information helps but please don't hesitate to contact me should you require any additional assistance.

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