HRP Anti-Mycobacterium tuberculosis antibody (ab21189)
Key features and details
- HRP Rabbit polyclonal to Mycobacterium tuberculosis
- Suitable for: IHC-P
- Conjugation: HRP
- Isotype: IgG
Overview
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Product name
HRP Anti-Mycobacterium tuberculosis antibody
See all Mycobacterium tuberculosis primary antibodies -
Description
HRP Rabbit polyclonal to Mycobacterium tuberculosis -
Host species
Rabbit -
Conjugation
HRP -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mycobacterium tuberculosis -
Immunogen
Tissue, cells or virus corresponding to Mycobacterium tuberculosis. Mycobacterium tuberculosis purified protein derivative
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General notes
IgG fraction covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while reserving maximum enzyme activity. Free enzyme is absent. Estimated Molar HRP: IgG substitution is 2-3
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
IgG fraction -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab21189 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent dilution.
|
Notes |
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IHC-P
Use at an assay dependent dilution. |
Target
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Relevance
Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method. -
Alternative names
- M. tuberculosis antibody
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab21189 has not yet been referenced specifically in any publications.