Key features and details
- HRP Goat polyclonal to Nitro tyrosine
- Conjugation: HRP
- Isotype: IgG
Product nameHRP Anti-Nitro tyrosine antibody
See all Nitro tyrosine primary antibodies
DescriptionHRP Goat polyclonal to Nitro tyrosine
Chemical/ Small Molecule (nitrotyrosine modified protein)
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.134% PBS, 0.58% Sodium chloride
Concentration information loading...
Purification notesPurified by nitrated protein-Sepharose™ affinity column.
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
- TMB ELISA Substrate (High Sensitivity) (ab171523)
- TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
- TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
- TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
- TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
- 450 nm Stop Solution for TMB Substrate (ab171529)
- 650 nm Stop Solution for TMB Substrate (ab171531)
- Immunoassay Blocking Buffer (ab171534)
- Immunoassay Blocking (BSA Free) (ab171535)
WB: 1/1000 - 1/4000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceNitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
- NO tyrosine antibody
- nTyr antibody
ab27648 has been referenced in 1 publication.
- Tang Z et al. Sensitive immunoassays of nitrated fibrinogen in human biofluids. Talanta 81:1662-9 (2010). ELISA . PubMed: 20441955