HRP Anti-Plasmodium aldolase antibody (ab38905)
Key features and details
- HRP Rabbit polyclonal to Plasmodium aldolase
- Suitable for: WB, ELISA
- Reacts with: Species independent
- Conjugation: HRP
- Isotype: IgG
Overview
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Product name
HRP Anti-Plasmodium aldolase antibody
See all Plasmodium aldolase primary antibodies -
Description
HRP Rabbit polyclonal to Plasmodium aldolase -
Host species
Rabbit -
Conjugation
HRP -
Tested applications
Suitable for: WB, ELISAmore details -
Species reactivity
Reacts with: Species independent -
Immunogen
Recombinant full length plasmodium aldolase.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.2% BSA, 0.58% Sodium chloride, 1.19% HEPES -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Related Products
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Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab38905 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | (1) |
Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.
|
| ELISA |
Use a concentration of 0.5 µg/ml.
|
| Notes |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. |
|
ELISA
Use a concentration of 0.5 µg/ml. |
Target
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Relevance
Malaria caused by Plasmodium falciparum remains the major life-threatening parasitic infection in the world. Plasmodium aldolase is an enzyme of the parasite glycolytic pathway expressed by the blood stages of Plasmodium falciparum as well as the non-falciparum malaria parasites. Monoclonal antibodies against Plasmodium aldolase are pan-specific in their reaction and have been used in an immunochromatographic test that targets the pan malarial antigen to rapidly detect malaria cases. CATALYTIC ACTIVITY: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. -
Cellular localization
Cytoplasmic
Datasheets and documents
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SDS download
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Datasheet download
References (14)
ab38905 has been referenced in 14 publications.
- Painter HJ et al. Atypical Molecular Basis for Drug Resistance to Mitochondrial Function Inhibitors in Plasmodium falciparum. Antimicrob Agents Chemother 65:N/A (2021). PubMed: 33361312
- Pandey R et al. Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission. Cell Rep 30:1883-1897.e6 (2020). PubMed: 32049018
- Bryant JM et al. Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite. Mol Syst Biol 16:e9569 (2020). PubMed: 32816370
- Baumgarten S et al. Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development. Nat Microbiol 4:2246-2259 (2019). PubMed: 31384004
- Istvan ES et al. Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis. Elife 8:N/A (2019). PubMed: 30888318