Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab210694 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab210694 in the following tested applications.
|WB||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 35 kDa).
1 hour primary incubation is recommended for this product.
FunctionFavors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
PathwayHormone biosynthesis; testosterone biosynthesis.
Involvement in diseaseDefects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH) [MIM:264300]. These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place.
Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
- Information by UniProt
- 17 @beta HSD III antibody
- 17 beta HSD 3 antibody
- 17-@beta hydroxysteroid dehydrogenase III antibody
Anti-HSD17B3 antibody (ab210694) at 2 µg/ml + Human testis lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 35 kDa
Observed band size: 33 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour.
ab210694 has not yet been referenced specifically in any publications.