Key features and details
- Rabbit polyclonal to HSD17B4
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-HSD17B4 antibody
See all HSD17B4 primary antibodies
DescriptionRabbit polyclonal to HSD17B4
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Guinea pig, Cow, Pig, Zebrafish
Recombinant fragment corresponding to Human HSD17B4 aa 18-231.
Database link: P51659
- WB: HeLa, Mouse brain whole cell lysate IHC-P: Human ovarian cancer. ICC/IF: HeLa cells.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
Our Abpromise guarantee covers the use of ab97971 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 80 kDa.|
|IHC-P||1/100 - 1/1000.|
|ICC/IF||1/100 - 1/1000.|
FunctionBifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Tissue specificityPresent in many tissues with highest concentrations in liver, heart, prostate and testis.
PathwayLipid metabolism; fatty acid beta-oxidation.
Involvement in diseaseD-bifunctional protein deficiency
Perrault syndrome 1
Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
Contains 1 MaoC-like domain.
Contains 1 SCP2 domain.
- Information by UniProt
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Paraffin embedded human ovarian cancer tissue stained for HSD17B4 using ab97971 at 1/500 dilution in immunohistochemical analysis.
HeLa cells stained for HSD17B4 (green) using ab97971 at 1/500 dilution in ICC/IF.
Anti-HSD17B4 antibody (ab97971) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 80 kDa
7.5% SDS PAGE
Anti-HSD17B4 antibody (ab97971) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg
Predicted band size: 80 kDa
7.5% SDS PAGE
ab97971 has been referenced in 1 publication.
- Shi X & Fu L Piceatannol inhibits oxidative stress through modification of Nrf2-signaling pathway in testes and attenuates spermatogenesis and steroidogenesis in rats exposed to cadmium during adulthood. Drug Des Devel Ther 13:2811-2824 (2019). PubMed: 31496657