Key features and details
- Rabbit polyclonal to HSD17B7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-HSD17B7 antibody
See all HSD17B7 primary antibodies
DescriptionRabbit polyclonal to HSD17B7
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment, corresponding to amino acids 35-221 of Human HSD17B7 (BC007068).
- 293T and MCF7 cell lysates.
FormLyophilized:Reconstitute in 200ul Steriled Distilled Water.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab112006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 38 kDa).|
FunctionResponsible for the reduction of the keto group on the C-3 of sterols.
Tissue specificityHighly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.
PathwaySteroid biosynthesis; estrogen biosynthesis.
Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 5/6.
Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- 17 beta HSD 7 antibody
- 17 beta hydroxysteroid dehydrogenase 7 antibody
- 17 beta hydroxysteroid dehydrogenase type VII antibody
ab112006 has been referenced in 1 publication.
- Wang X et al. Synergistic control of sex hormones by 17ß-HSD type 7: a novel target for estrogen-dependent breast cancer. J Mol Cell Biol 7:568-79 (2015). PubMed: 25966904