Overview

  • Product name
    Anti-HSD3B1 antibody [EPR9687]
    See all HSD3B1 primary antibodies
  • Description
    Rabbit monoclonal [EPR9687] to HSD3B1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human HSD3B1 (UniProt: P14060)

  • Positive control
    • Human placenta cell lysate, Caco-2 cells.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab167417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 42 kDa.
ICC/IF 1/250 - 1/500.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
    • Tissue specificity
      Placenta and skin. Predominantly expressed in mammary gland tissue.
    • Pathway
      Lipid metabolism; steroid biosynthesis.
    • Sequence similarities
      Belongs to the 3-beta-HSD family.
    • Cellular localization
      Endoplasmic reticulum membrane. Mitochondrion membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3 beta and steroid delta isomerase 1 antibody
      • 3 beta and steroid hydroxy delta 5 steroid dehydrogenase antibody
      • 3 beta HSD I antibody
      • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I antibody
      • 3-beta-HSD I antibody
      • 3-beta-hydroxy-5-ene steroid dehydrogenase antibody
      • 3BETAHSD antibody
      • 3BH antibody
      • 3BHS1_HUMAN antibody
      • 3BHSD antibody
      • Delta-5-3-ketosteroid isomerase antibody
      • HGNC:5217 antibody
      • HSD3B antibody
      • HSD3B1 antibody
      • HSDB3 antibody
      • HSDB3A antibody
      • Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1 antibody
      • Hydroxy delta 5 steroid dehydrogenase antibody
      • Progesterone reductase antibody
      • SDR11E1 antibody
      • Steroid Delta-isomerase antibody
      • trophoblast antigen antibody
      • Trophoblast antigen FDO161G antibody
      see all

    Images

    • Anti-HSD3B1 antibody [EPR9687] (ab167417) at 1/1000 dilution + Human placenta cell lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP antibody at 1/2000 dilution

      Predicted band size: 42 kDa

    • Immunofluorescent analysis of Caco-2 cells labeling HSD3B1 with ab167417 at 1/250 dilution.

    References

    ab167417 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab167417.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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