Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Constituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab169172 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa.|
|ICC/IF||Use a concentration of 10 µg/ml.|
FunctionMay be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
Tissue specificityPredominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.
Sequence similaritiesContains 1 SH2 domain.
modificationsMay be phosphorylated by FES and ACK1.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- Adaptor in lymphocytes of unknown function X antibody
- ALX antibody
- FLJ14886 antibody
All lanes : Anti-HSH2D antibody (ab169172) at 1 µg/ml
Lane 1 : HSH2D transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
All lanes : Goat anti-mouse HRP at 1/2500 dilution
Predicted band size: 39 kDa
Immunocytochemistry/Immunofluorescence analysis of HeLa cells labeling HSH2D with ab169172 at 10µg/ml.
ab169172 has not yet been referenced specifically in any publications.