Key features and details
- Rabbit polyclonal to Hsp90 (Biotin)
- Suitable for: WB, ELISA, RIA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
Product nameAnti-Hsp90 antibody (Biotin)
See all Hsp90 primary antibodies
DescriptionRabbit polyclonal to Hsp90 (Biotin)
Tested applicationsSuitable for: WB, ELISA, RIAmore details
Species reactivityReacts with: Human
Recombinant full length Hsp90 protein (Human) expressed in E. coli.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.50
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab79649 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 83 kDa.|
|ELISA||Use a concentration of 3 - 8 µg/ml.|
|RIA||Use a concentration of 3 - 8 µg/ml.|
FunctionMolecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Sequence similaritiesBelongs to the heat shock protein 90 family.
DomainThe TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins like the co-chaperone STUB1.
S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1.
Cellular localizationCytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- Information by UniProt
- Heat shock 86 kDa antibody
- Heat shock protein 90kDa alpha cytosolic class A member 1 antibody
- Heat shock protein 90kDa alpha cytosolic class B member 1 antibody
ab79649 has not yet been referenced specifically in any publications.