Anti-HSV1 gC Envelope Protein antibody [3G9] (ab6509)
Key features and details
- Mouse monoclonal [3G9] to HSV1 gC Envelope Protein
- Suitable for: WB, ELISA, ICC/IF
- Reacts with: Herpes simplex virus
- Isotype: IgG2a
Overview
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Product name
Anti-HSV1 gC Envelope Protein antibody [3G9] -
Description
Mouse monoclonal [3G9] to HSV1 gC Envelope Protein -
Host species
Mouse -
Tested applications
Suitable for: WB, ELISA, ICC/IFmore details -
Species reactivity
Reacts with: Herpes simplex virus -
Immunogen
Tissue, cells or virus corresponding to Herpes simplex virus HSV1 gC Envelope Protein. Herpes Virus
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4 -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
3G9 -
Myeloma
NS1/1-Ag4-1 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab6509 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (2) |
1/1000.
|
ELISA |
1/102400.
|
|
ICC/IF |
1/25600.
|
Notes |
---|
WB
1/1000. |
ELISA
1/102400. |
ICC/IF
1/25600. |
Target
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Relevance
Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. -
Database links
- Entrez Gene: 2703410 Herpes simplex virus
- SwissProt: P10228 Herpes simplex virus
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Alternative names
- Envelope glycoprotein C antibody
- GC antibody
- Glycoprotein C antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (13)
ab6509 has been referenced in 13 publications.
- DiScipio KA et al. Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses. mBio 13:e0322621 (2022). PubMed: 35073739
- Murray-Nerger LA et al. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res 49:2044-2064 (2021). PubMed: 33533922
- Kristen H et al. LAMP2 deficiency attenuates the neurodegeneration markers induced by HSV-1 infection. Neurochem Int 146:105032 (2021). PubMed: 33781848
- Llorente P et al. Matrix metalloproteinase 14 regulates HSV-1 infection in neuroblastoma cells. Antiviral Res 192:105116 (2021). PubMed: 34107282
- Saiz-Ros N et al. Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication. Cells 8:N/A (2019). PubMed: 30717447