Key features and details
- Rabbit polyclonal to HTR3C
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-HTR3C antibody
DescriptionRabbit polyclonal to HTR3C
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Fusion protein corresponding to Human HTR3C (internal sequence). BC131799; The identity of the protein fusion partner is GST.
Database link: Q8WXA8
- HT29 cell lysate; Human prostate cancer tissue.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab199148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||1/200 - 1/1000. Predicted molecular weight: 50 kDa.|
RelevanceHTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
Cellular localizationCell Membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A
- 5 HT3 C antibody
- 5 HT3C antibody
- 5 hydroxytryptamine (serotonin) receptor 3, family member C antibody
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue labeling HTR3C with ab199148 at 1/30 dilution.
Anti-HTR3C antibody (ab199148) at 1/500 dilution + HT29 cell lysate at 40 µg
Developed using the ECL technique.
Predicted band size: 50 kDa
Exposure time: 20 seconds
ab199148 has not yet been referenced specifically in any publications.