Key features and details
- Mouse monoclonal [16C12AA10] to HuD
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG2b
Product nameAnti-HuD antibody [16C12AA10]
See all HuD primary antibodies
DescriptionMouse monoclonal [16C12AA10] to HuD
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
Does not react with: Mouse, Rat, Cow
- ELAVL4 recombinant protein.
Product was previously marketed under the MitoSciences sub-brand.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% HEPES buffered saline
Concentration information loading...
Light chain typekappa
Our Abpromise guarantee covers the use of ab171448 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 2 µg/ml. Predicted molecular weight: 42 kDa.|
|ELISA||Use a concentration of 1 µg/ml.|
FunctionMay play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA.
Sequence similaritiesBelongs to the RRM elav family.
Contains 3 RRM (RNA recognition motif) domains.
modificationsMethylation at Arg-243 by CARM1 weakens protective binding to the 3'-UTR of CDKN1A mRNA and down-regulates CDKN1A protein expression, thereby maintaining cells in a proliferative state. Methylation is inhibited by NGF, which facilitates neurite outgrowth.
- Information by UniProt
- ELAV (embryonic lethal abnormal vision Drosophila) like 4 antibody
- ELAV L4 antibody
- ELAV like 4 antibody
Anti-HuD antibody [16C12AA10] (ab171448) at 2 µg/ml + Human ELAV4 recombinant protein at 0.100000001490116 µg
Goat polyclonal to Mouse IgG - HRP at 1/5000 dilution
Predicted band size: 42 kDa
Analysis demonstrating the specificity of ab171448 using the ELISA platform.
Antibody concentration is at 1 µg/mL, the concentration of recombinant proteins is at 250 ng/mL. The antibody reacts specifically to HuD/ELAV4 protein.
ab171448 has not yet been referenced specifically in any publications.