Product nameHuman Actin Regulatory Protein CAPG/MCP peptide
See all Actin Regulatory Protein CAPG/MCP proteins and peptides
Purity70 - 90% by HPLC.
Our Abpromise guarantee covers the use of ab101225 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
This product was previously labelled as Actin Regulatory Protein CAPG
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- Actin capping protein GCAP39
- Actin regulatory protein CAP G
- Actin regulatory protein CAP-G
FunctionCalcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Tissue specificityMacrophages and macrophage-like cells.
Sequence similaritiesBelongs to the villin/gelsolin family.
Contains 3 gelsolin-like repeats.
modificationsThe N-terminus is blocked.
Cellular localizationCytoplasm. Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab101225 has not yet been referenced specifically in any publications.