Human AGAP1 peptide (ab23095)

Our Abpromise guarantee covers the use of ab23095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Alternative names
- AGAP 1
- AGAP-1
- Agap1
- AGAP1_HUMAN
- Arf GAP with GTP binding proteinlike ANK repeat and PH domains 1
- Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
- ArfGAP with GTPase domain ankyrin repeat and PH domain 1
- Centaurin gamma 2
- Centaurin-gamma-2
- CENTG2
- Cnt-g2
- GGAP 1
- GGAP1
- GTP binding and GTPase activating protein 1
- GTP-binding and GTPase-activating protein 1
- KIAA1099
- MGC71657
see all
Function

GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
Tissue specificity

Widely expressed.
Sequence similarities

Belongs to the centaurin gamma-like family.
Contains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.
Domain

The PH domain mediates AP-3 binding.
Post-translational
modifications

Phosphorylated on tyrosines.
Cellular localization

Cytoplasm. Associates with the endocytic compartment.
Target information above from: UniProt accession Q9UPQ3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

ab23095 has not yet been referenced specifically in any publications.

Publishing research using ab23095? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"